Olive Oil Consumption and Bone Microarchitecture in Spanish Women

Roncero-Martín, Raúl; Vera, Ignacio Aliaga; Corral, Luis Javier Moreno; Morán, José María Tovillas; Lavado‐García, Jesus M.; Pedrera‐Zamorano, Juan D.; Pedrera-Canal, María

doi:10.3390/nu10080968

Cited by 22 publications

(20 citation statements)

References 28 publications

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“…A dose-dependent protective effect of oleuropein, which is a polyphenol from olive oil, has been found in an in vivo experimental model of rats with bone loss [19]. A recent study concluded that the dietary intake of olive oil is positively associated with total, trabecular, and cortical BMD [50].…”

Section: Discussionmentioning

confidence: 99%

Adherence to a Mediterranean Diet and Bone Mineral Density in Spanish Premenopausal Women

et al. 2019

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The Mediterranean diet (MD) has been associated with an improvement in health and an increase in longevity. Certain components of a MD can play a role in the prevention of osteoporosis and/or hip fracture. We investigated the association between the degree of adherence to a MD and bone mineral density (BMD) measured in several bone areas in a population of Spanish premenopausal women. We analyzed 442 premenopausal women aged 42.73 ± 6.67 years. Bone measurements were obtained using quantitative bone ultrasound (QUS) for the phalanx, dual energy X-ray absorptiometry (DXA) for the lumbar spine, Ward’s triangle, trochanter, and hip, and peripheral quantitative computed tomography (pQCT) for the non-dominant distal forearm. MD adherence was evaluated with MedDietScore. Amplitude-dependent speed of sound (Ad-SOS), BMD, and volumetric bone mineral density (vBMD) (total, trabecular, and cortical bone density) were positively associated with higher adherence to the MD (p < 0.05). Adherence to the MD was significantly associated with QUS, BMD, and vBMD in multiple regression analysis; QUS: Ad-SOS (m/s) β = 0.099 (p = 0.030); BMD (g/cm2): femur neck β = 0.114 (p = 0.010) and Ward’s triangle β = 0.125 (p = 0.006); vBMD (mg/cm3): total density β = 0.119 (p = 0.036), trabecular density β = 0.120 (p = 0.035), and cortical density β = 0.122 (p = 0.032). We conclude that the adherence to the MD was positively associated with better bone mass in Spanish premenopausal women.

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Section: Discussionmentioning

confidence: 99%

Adherence to a Mediterranean Diet and Bone Mineral Density in Spanish Premenopausal Women

et al. 2019

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“…It has been demonstrated that the phenolic compounds can modulate the growing capacity and cell maturation of osteoblasts by increasing alkaline phosphatase activity and contributing to the creation of the extracellular matrix. The dietary intake of olive oil was significantly associated with higher BMD in a cohort of Spanish women across a wide range of ages [73]. Furthermore, it was associated with a higher total osteocalcin concentration and an increase in procollagen I N-terminal propeptide in a group of men, suggesting the protective effects of olive oil on bone [74].…”

Section: Mediterranean Dietmentioning

confidence: 90%

Nutrients and Dietary Patterns Related to Osteoporosis

2020

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Osteoporosis is a common chronic disease characterized by a decrease in bone mineral density, impaired bone strength, and an increased risk of fragility fractures. Fragility fractures are associated with significant morbidity, mortality and disability and are a major public health problem worldwide. The influence of nutritional factors on the development and progression of this disease can be significant and is not yet well established. Calcium intake and vitamin D status are considered to be essential for bone metabolism homeostasis. However, some recent studies have questioned the usefulness of calcium and vitamin D supplements in decreasing the risk of fractures. The adequate intake of protein, vegetables and other nutrients is also of interest, and recommendations have been established by expert consensus and clinical practice guidelines. It is important to understand the influence of nutrients not only in isolation but also in the context of a dietary pattern, which is a complex mixture of nutrients. In this review, we evaluate the available scientific evidence for the effects of the main dietary patterns on bone health. Although some dietary patterns seem to have beneficial effects, more studies are needed to fully elucidate the true influence of diet on bone fragility.

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“…That is partially due to the effects of its phenolic components on osteoblastic differentiation of MSCs. Therefore, it has been proposed that intake of this food, as well as other products derived from the olive tree, may help to prevent bone mass loss, due to diseases like osteoporosis[142,143] or physiological aging.…”

Section: Effects Of Unsaponifiable Fraction Of Olive Oil In Mscsmentioning

confidence: 99%

Influence of olive oil and its components on mesenchymal stem cell biology

Casado-Díaz¹,

Dorado²,

Quesada‐Gómez³

2019

WJSC

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Extra virgin olive oil is characterized by its high content of unsaturated fatty acid residues in triglycerides, mainly oleic acid, and the presence of bioactive and antioxidant compounds. Its consumption is associated with lower risk of suffering chronic diseases and unwanted processes linked to aging, due to the antioxidant capacity and capability of its components to modulate cellular signaling pathways. Consumption of olive oil can alter the physiology of mesenchymal stem cells (MSCs). This may explain part of the healthy effects of olive oil consumption, such as prevention of unwanted aging processes. To date, there are no specific studies on the action of olive oil on MSCs, but effects of many components of such food on cell viability and differentiation have been evaluated. The objective of this article is to review existing literature on how different compounds of extra virgin olive oil, including residues of fatty acids, vitamins, squalene, triterpenes, pigments and phenols, affect MSC maintenance and differentiation, in order to provide a better understanding of the healthy effects of this food. Interestingly, most studies have shown a positive effect of these compounds on MSCs. The collective findings support the hypothesis that at least part of the beneficial effects of extra virgin olive oil consumption on health may be mediated by its effects on MSCs.

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Olive Oil Consumption and Bone Microarchitecture in Spanish Women

Cited by 22 publications

References 28 publications

Adherence to a Mediterranean Diet and Bone Mineral Density in Spanish Premenopausal Women

Adherence to a Mediterranean Diet and Bone Mineral Density in Spanish Premenopausal Women

Nutrients and Dietary Patterns Related to Osteoporosis

Influence of olive oil and its components on mesenchymal stem cell biology

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