Omega-3 fatty acids and exercise: a review of their combined effects on body composition and physical performance

Abstract

SummaryOmega-3 (n-3) fatty acids, and the long-chain n-3 derivatives eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in particular, have been extensively researched for their nutritive effects. Among their many purported benefits, n-3 acids have been implicated as positive mediators of cardiovascular health and body composition. It has therefore been speculated that supplementation may enhance the beneficial effects of physical activity, potentiating greater reductions in body fat and improvements in exercise performance. This paper has three objectives: first, to assess the theoretical basis for a synergistic ef-fect when n-3 supplementation is combined with exercise; second, to review the literature as to specific findings on the subject and third, to make relevant conclusions and recommendations for future research.

Obesity polymorphisms identified in genome-wide association studies interact with n-3 polyunsaturated fatty acid intake and modify the genetic association with adiposity phenotypes in Yup’ik people

“…After corrections for n-3 PUFA consumption, we found rs9939609 (FTO) was positively associated PBF and rs7647305 (ETV5) was negatively associated with ThC and HC. Interestingly, controlled feeding studies in rodents have shown that n-3 PUFAs decrease adiposity by reducing central fat mass (Tiryaki-Sönmez et al 2011); however, epidemiological evidence in humans supporting the antiobesity effects of n-3 PUFAs remains controversial and is often limited to n-3 PUFA supplementation studies (Buckley and Howe 2010). Our analyses indicate that genetic predisposition to obesity, as measured by the GRS, was positively associated with adiposity and interactions …”

Cancer cachexia: impact, mechanisms and emerging treatments

“…It has further been confirmed that EPA-associated weight gain or stabilisation in cachectic patients is not due to water retention [186, 193]. EPA’s amelioration of cachexia has been shown to be particularly effective in the presence of a targeted exercise regime [77, 200, 201], supporting the inclusion of physical activity in multimodality treatments.…”

Impact of Omega-3 PUFAs Supplementation with Lifestyle Modification on Anthropometric Indices and Vo2 max in Overweight Women

“…As per the outcomes, body weight, muscle to fat ratio ratios percent, and stomach perimeter and stomach skinfold thickness decreased in omega 3 treated gatherings at 8 weeks after start of study. A substantial number of both trial and epidemiological studies have subsequent to been directed to analyze the impact of devouring fish oil, which contains high measure of n-3 acids, on health [13].…”

“…Moreover, omega-3 PUFAs supplementation expanded cytoplasmic unsaturated fat tying protein substance and fat oxidation in rats [14]. Additionally, a huge lessening in muscle to fat ratio ratios was seen by supplementation of fish oil (50 ml) for 12 weeks in addition to practice contrasted with activity just group [13]. People groups [15] reported male cyclists treated with fish oil (8 g/day for 8 weeks) essentially had lower heart rates amid incremental workloads to weariness and entire body oxygen utilization however without critical effect on top oxygen utilization.…”

“…Proofs bolster the connection between the n-3 unsaturated fats (FAs) utilization, practice and weight reduction which omega-3 PUFAs utilization could expand execution amid continuance exercise [12,13]. It was accounted for amid cycling sessions (60% of VO 2 max) the omega-3 PUFAs supplementation diminished plasma glucose vanishing rate and hepatic glucose creation, and also glucose metabolic leeway rate contrasted with controls [14].…”