2024
DOI: 10.5935/1518-0557.20240033
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Omega 3 fatty acids preserve testicular function by ameliorating BPF-induced dysthyroidism: role of p53/Bcl-2 signaling and proton pump activities

Adeyemi Fatai Odetayo,
Luqman Aribidesi Olayaki

Abstract: Objective: Bisphenol F (BPF) is an endocrinedisrupting chemical, but information about its effect on thyroid hormones has not been fully explored. Omega 3 fatty acids (O3FA), on the other hand, are antioxidant and antiapoptotic agents. Therefore, this study explored the role and associated molecular mechanism of O3FA in BPFinduced hypothyroidism-mediated testicular dysfunction in male Wistar rats.Methods: Twenty (20) male Wistar rats were randomized into four groups (n=5/group), namely: the control group; the … Show more

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