Omental Transplantation for Critical Limb Ischemia in Buerger???s Disease

Bhat, Mohd Akbar; Zaroo, Mohammad Inam; Darzi, MA

doi:10.1097/01.prs.0000259775.68749.4a

Cited by 7 publications

(3 citation statements)

References 3 publications

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“…For patients with no‐option critical limb ischaemia disease, there are few treatment options. Some studies have reported that effective treatment can be achieved through methods such as venous‐arterialisation, 47 autologous stem cell transplantation, 48 omentum majus transplantation 49 and bioengineering materials 50 . Although most of these techniques are generally applicable for chronic lower limb ischaemia, they may not always be suitable for diabetic foot ulcers complicated with lower extremity vasculopathy because of the limited time for treatment. Endovascular therapy Endovascular therapy primarily comprises balloon dilatation, stent plasty, atherectomy, ultrasound ablation, cutting balloon plasty and laser‐assisted angioplasty.…”

Section: Resultsmentioning

confidence: 99%

Diagnosis and treatment of diabetic foot ulcer complicated with lower extremity vasculopathy: Consensus recommendation from the Chinese Medical Association (CMA), Chinese Medical Doctor Association (CMDA)

Wang,

Shi

et al. 2024

Diabetes Metabolism Res

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Diabetic foot ulcer complicated with lower extremity vasculopathy is highly prevalent, slow healing and have a poor prognosis. The final progression leads to amputation, or may even be life‐threatening, seriously affecting patients' quality of life. The treatment of lower extremity vasculopathy is the focus of clinical practice and is vital to improving the healing process of diabetic foot ulcers. Recently, a number of clinical trials on diabetic foot ulcers with lower extremity vasculopathy have been reported. A joint group of Chinese Medical Association (CMA) and Chinese Medical Doctor Association (CMDA) expert representatives reviewed and reached a consensus on the guidelines for the clinical diagnosis and treatment of this kind of disease. These guidelines are based on evidence from the literature and cover the pathogenesis of diabetic foot ulcers complicated with lower extremity vasculopathy and the application of new treatment approaches. These guidelines have been put forward to guide practitioners on the best approaches for screening, diagnosing and treating diabetic foot ulcers with lower extremity vasculopathy, with the aim of providing optimal, evidence‐based management for medical personnel working with diabetic foot wound repair and treatment.

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Section: Resultsmentioning

confidence: 99%

Diagnosis and treatment of diabetic foot ulcer complicated with lower extremity vasculopathy: Consensus recommendation from the Chinese Medical Association (CMA), Chinese Medical Doctor Association (CMDA)

Wang,

Shi

et al. 2024

Diabetes Metabolism Res

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“…In addition, postoperative angiography showed increased collateral vessels, suggesting that the greater omentum plays a positive role in the treatment of buerger's disease by providing additional blood vessels for ischemic muscle and generating angiogenesis through the production of vascular growth factor [104]. Another study showed that three patients have improved clinical function after omental transposition, including pain alleviation and increased walking distance, based on the function of omental transfer to promote blood vessel synthesis and increase tissue perfusion [105](Table 1).…”

Section: Buerger's Diseasementioning

confidence: 99%

The Greater Omentum: Multifaceted Interactions in Neurological Recovery and Disease Progression

2024

Aging dis

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The greater omentum, a unique anatomical structure composed of adipocytes, loose connective tissue, and a dense vascular network. Plays a pivotal role beyond its traditional understanding. It houses specialized immunological units known as 'Milky spots,' making it a key player in immune response. Moreover, the omentum's capacity to enhance tissue perfusion, absorb edema fluid, boost acetylcholine synthesis, and foster neuron repair have rendered it a topic of interest in the context of various diseases, especially neurological disorders. This review provides a comprehensive overview of the intricate anatomy and histology of the greater omentum, casting light on its multifaceted functions and its associations with a spectrum of diseases. With a specific focus on neurological ailments, we delineate the intricate relationship that the omentum shares with other pathologies like stroke and we underly its contribution to serving as a therapeutic agent in neurological disorders. By deciphering the underlying mechanisms and emphasizing areas that demand further investigation. This review aims to spark renewed interest and pave the way for comprehensive studies exploring the greater omentum's potential in neurology and broader medicine overall. Given these diverse interactions that yet remain elusive, we must investigate and understand the nuanced relationship between the greater omentum and pathologies, especially its role in stroke's pathophysiology and therapeutic interventions so as to enhance patient care.

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“…29 Omentum has long been appreciated to produce angiogenic factors that can be beneficial to healing. 30,31 The omentum has been found to improve wound healing and perfusion in Buerger disease in the lower extremity 32 ; this has been applied as a pedicled flap from the abdomen with the omentum stretched out into the leg 33,34 as well as a free flap in some instances. 35 This tissue has also been applied to the upper extremity as a pedicled flap (with later division of the pedicle) with surprisingly good results.…”

Section: Vascularized Omental Transfermentioning

confidence: 99%

Revascularization Options for Terminal Distal Ischemia

Pederson

2015

Hand Clinics

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Omental Transplantation for Critical Limb Ischemia in Buerger???s Disease

Cited by 7 publications

References 3 publications

Diagnosis and treatment of diabetic foot ulcer complicated with lower extremity vasculopathy: Consensus recommendation from the Chinese Medical Association (CMA), Chinese Medical Doctor Association (CMDA)

Diagnosis and treatment of diabetic foot ulcer complicated with lower extremity vasculopathy: Consensus recommendation from the Chinese Medical Association (CMA), Chinese Medical Doctor Association (CMDA)

The Greater Omentum: Multifaceted Interactions in Neurological Recovery and Disease Progression

Revascularization Options for Terminal Distal Ischemia

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