Omeprazole‐induced hypertrichosis in two children

Abstract

Omeprazole significantly increases duodenal prostaglandin E synthesis. Prostaglandins are involved in hair growth regulation: prostaglandin E and prostaglandin F alpha stimulate hair growth, and prostaglandin D has an inhibitory effect. The use of omeprazole can cause acquired generalized hypertrichosis by increasing prostaglandin E levels.