Omics Approaches in Marine Biotechnology

Abid, Fatima; Zahid, Maryam; Abedin, Zain U.; Nizami, Syed B.; Abid, Muhammad J.; Kazmi, Sayyada Z. Hassan; Khan, Sami Ullah; Hasan, Humna; Ali, Mohsin; Gul, Alvina

doi:10.1016/b978-0-12-804659-3.00003-8

Cited by 4 publications

(5 citation statements)

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“…This branch of omics focuses on studying the metabolomes (low molecular weight metabolites produced internally in the tissues, cells, or fluids) of the organisms [97]. It allows the identification of useful biological metabolites produced at normal conditions or under stressful environmental conditions [97]. This is because the metabolome is a product of gene expression and protein production which are directly affected by physiological and environmental inductions [98].…”

Section: Metabolomicsmentioning

confidence: 99%

“…Unlike other omics approaches, metabolomics faces the difficulty of measuring and identifying the produced metabolites since they have diversified physiochemical characteristics [97]. Thus, the metabolites identification process does not have a specific bioanalytical tool.…”

Section: Metabolomicsmentioning

confidence: 99%

Section: Marine Microbial Bioprospectingmentioning

confidence: 99%

“…For instance, if one is considering the proteomics approach, then the results will be restricted to the detectable proteins, where proteins of low concentrations are not likely to be identified [102]. Looking into metabolomics, the detection of metabolites often requires utilizing more than one detection tool to cover most metabolites [97]. Generally, it is recommended to combine more than one approach to have an idea of the genetic coding and the corresponding produced molecule, to facilitate future application.…”

Section: Marine Microbial Bioprospectingmentioning

confidence: 99%

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Marine microbial bioprospecting: Exploitation of marine biodiversity towards biotechnological applications—a review

et al. 2022

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The increase in the human population causes an increase in the demand for nutritional supplies and energy resources. Thus, the novel, natural, and renewable resources became of great interest. Here comes the optimistic role of bioprospecting as a promising tool to isolate novel and interesting molecules and microorganisms from the marine environment as alternatives to the existing resources. Bioprospecting of marine metabolites and microorganisms with high biotechnological potentials has gained wide interest due to the variability and richness of the marine environment. Indeed, the existence of extreme conditions that increases the adaptability of marine organisms, especially planktons, allow the presence of interesting biological species that are able to produce novel compounds with multiple health benefits and high economical value. This review aims to provide a comprehensive overview of marine microbial bioprospecting as a growing field of interest. It emphasizes functional bioprospecting that facilitates the discovery of interesting metabolites. Marine bioprospecting was also discussed from a legal aspect for the first time, focusing on the shortcomings of international law. We also summarized the challenges facing bioprospecting in the marine environment including economic feasibility issues.

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Section: Metabolomicsmentioning

confidence: 99%

Section: Metabolomicsmentioning

confidence: 99%

Section: Marine Microbial Bioprospectingmentioning

confidence: 99%

Section: Marine Microbial Bioprospectingmentioning

confidence: 99%

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Marine microbial bioprospecting: Exploitation of marine biodiversity towards biotechnological applications—a review

et al. 2022

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“…“Omics” technologies are becoming increasingly involved in the development of biotechnological processes for the production of many substantial products. The use of “omics” technologies to characterize and understand biological systems has enabled researchers to select and predict phenotypes (Abid et al, 2018 ; Babar et al, 2018 ), which aids the optimization of biotechnological processes toward enhanced production (in quality and quantity) of commercially relevant products ( Figure 2 ). This section discusses the application of “omics” in the development of biofuels and bioproducts, agricultural biotechnology, food biotechnology, and bio-therapeutics.…”

Section: Omics-guided Biotechnologymentioning

confidence: 99%

Omics-Driven Biotechnology for Industrial Applications

Amer

Baidoo

2021

Front. Bioeng. Biotechnol.

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Biomanufacturing is a key component of biotechnology that uses biological systems to produce bioproducts of commercial relevance, which are of great interest to the energy, material, pharmaceutical, food, and agriculture industries. Biotechnology-based approaches, such as synthetic biology and metabolic engineering are heavily reliant on “omics” driven systems biology to characterize and understand metabolic networks. Knowledge gained from systems biology experiments aid the development of synthetic biology tools and the advancement of metabolic engineering studies toward establishing robust industrial biomanufacturing platforms. In this review, we discuss recent advances in “omics” technologies, compare the pros and cons of the different “omics” technologies, and discuss the necessary requirements for carrying out multi-omics experiments. We highlight the influence of “omics” technologies on the production of biofuels and bioproducts by metabolic engineering. Finally, we discuss the application of “omics” technologies to agricultural and food biotechnology, and review the impact of “omics” on current COVID-19 research.

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