Omics Based Screening of novel inhibitors against malignant pleural mesothelioma
Maryam Saleem,
Muhammad Waqas,
Bilal Ahmad
et al.
Abstract:Malignant pleural mesothelioma (MPM) is an aggressive cancer affecting the pleural membrane. It is characterized by its rarity and lethality, presenting limited treatment avenues. Vascular endothelial growth factor A (VEGF-A) is a crucial signaling protein that binds to and activates the VEGFR-2 (vascular endothelial growth factor receptor-2). This interaction initiates a signaling cascade promoting endothelial cell proliferation and migration, fostering the formation of new blood vessels and fueling tumor gro… Show more
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