Omphalocele and gastroschisis in the state of New York, 1992–1999

Salihu, Hamisu M.; Pierre-Louis, Bosny; Druschel, Charlotte M.; Kirby, Russell S.

doi:10.1002/bdra.10113

Cited by 92 publications

(132 citation statements)

References 35 publications

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“…Using popula- tion-based data on nearly 1000 cases from 11 states with active case-finding, Canfield et al (2006) reported that Hispanic women had a significantly higher unadjusted birth prevalence of gastroschisis compared with NHwhite women (PR, 1.25; 95% CI, 1.09-1.43). Likewise, a study investigating 308 cases in New York reported that, after adjusting for maternal age, Hispanic women were 1.5 times more likely to have an offspring affected by gastroschisis (95% CI, 1.12-2.00; Salihu et al, 2003). However, in a population-based study in California on nearly 1000 cases over 17 years, Vu et al (2008) reported that the effect of Hispanic ethnicity on gastroschisis risk was modified by maternal nativity.…”

Section: Discussionmentioning

confidence: 99%

“…Much of the variation among states can be attributed to the method of case ascertainment and the case definition. States that use active case finding and that include cases from fetal deaths and live births, such as North Carolina (Laughon et al, 2003) and Hawaii (Forrester and Merz, 1999a), report relatively high prevalence rates (4.5 and 3.0/10,000 live births, respectively), while New York (Salihu et al, 2003), which uses passive case finding among live born infants, reports a relatively low rate (1.4/10,000).…”

Section: Introductionmentioning

confidence: 99%

“…The prevalence is also increasing in the United States, where the population-based rate of gastroschisis repairs was twofold higher in 2003 than 1996, with increases occurring in each census region (Alvarez and Burd, 2007). Utah (Hougland et al, 2005), Hawaii (Forrester and Merz, 1999a), New York (Salihu et al, 2003), Tennessee (Collins et al, 2007), California (Vu et al, 2008), and North Carolina (Laughon et al, 2003) reported increasing prevalence rates over the past decade.…”

Section: Introductionmentioning

confidence: 99%

“…Young maternal age is the most consistently reported risk factor (Baerg et al, 2003;Feldkamp et al, 2007;Hougland et al, 2005;Saada et al, 2005). Other maternal factors that have been suspected to increase gastroschisis risk include maternal smoking, maternal use of vasoactive substances, low socioeconomic status, low pregnancy body mass index, and Hispanic ethnicity (Haddow et al, 1993;Torfs et al, 1994;Lam et al, 1999;Werler et al, 2002;Salihu et al, 2003;Saada et al, 2005;Canfield et al, 2006;Feldkamp et al, 2007;Stothard et al, 2009). More recently, maternal birthplace (nativity) has been reported to affect the risk of congenital malformations, including gastroschisis; foreign-born women have a lower risk of delivering an infant with gastroschisis than U.S.-born women (Zhu et al, 2006;Vu et al, 2008).…”

Section: Introductionmentioning

confidence: 99%

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Maternal nativity as a risk factor for gastroschisis: A population‐based study

Salemi

Pierre

Tanner

et al. 2009

Birth Defects Research

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BACKGROUND:The prevalence of gastroschisis is increasing in many parts of the world, although the etiology is largely unexplained. Young maternal age has been the only consistently identified, strong risk factor. The objective of this study was to examine the role of maternal nativity in relation to other suspected risk factors for gastroschisis in Florida. METHODS: We conducted a retrospective cohort study of singleton infants born in Florida from 1998-2003. Gastroschisis cases were identified from the Florida Birth Defects Registry. Demographic and perinatal data were obtained from birth records. Multivariable Poisson regression was used to estimate adjusted prevalence ratios (PRs) and 95% confidence intervals (CIs) for each factor of interest. RESULTS: The 6-year birth prevalence of gastroschisis was 3.26 per 10,000 live births, and the annual rate increased 41% during the study period. In addition to maternal age and marital status, maternal race/ethnicity and nativity were significantly associated with the risk of delivering an infant with gastroschisis. Compared with non-Hispanic white women, non-Hispanic black women had the lowest risk of delivering an infant with gastroschisis (PR, 0.19; 95% CI, 0.13-0.26), followed by Hispanic women (PR, 0.60; 95% CI, 0.43-0.83). Women born outside the United States were significantly less likely than U.S.-born women to deliver an infant with gastroschisis (PR, 0.59; 95% CI, 0.41-0.86). CONCLUSIONS: Although young maternal age remains a strong significant risk factor for gastroschisis in Florida, other factors such as maternal race/ ethnicity and nativity could be important in explaining the increasing prevalence of gastroschisis. Birth

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Maternal nativity as a risk factor for gastroschisis: A population‐based study

Salemi

Pierre

Tanner

et al. 2009

Birth Defects Research

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“…[5][6][7][8][9][10][11][12][13] Surgical advances have resulted in an improved survival rate for infants with certain congenital defects including diaphragmatic hernia, abdominal wall defects, esophageal atresia, and cyanotic heart defects. [14][15][16][17][18] Many of these children have systemic health problems including neurodevelopmental disabilities, gastrointestinal illnesses, pulmonary complications, musculoskeletal abnormalities, and nutritional deficits. [5][6][7]13,19,20 These conditions may require frequent hospital and subspecialty care.…”

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confidence: 99%

Increasing Prevalence of Medically Complex Children in US Hospitals

et al. 2010

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OBJECTIVE: In this study we used national data to determine changes in the prevalence of hospital admissions for medically complex children over a 15-year period. PATIENTS AND METHODS: Data from the Nationwide Inpatient Sample, a component of the Healthcare Cost and Utilization Project, was analyzed in 3-year increments from 1991 to 2005 to determine national trends in rates of hospitalization of children aged 8 days to 4 years with chronic conditions. Discharge diagnoses from the Nationwide Inpatient Sample were grouped into 9 categories of complex chronic conditions (CCCs). Hospitalization rates for each of the 9 CCC categories were studied both individually and in combination. Trends of children hospitalized with 2 specific disorders, cerebral palsy (CP) and bronchopulmonary dysplasia, with additional diagnoses in more than 1 CCC category were also examined. RESULTS: Hospitalization rates of children with diagnoses in more than 1 CCC category increased from 83.7 per 100 000 (1991–1993) to 166 per 100 000 (2003–2005) (P[r] < .001). The hospitalization rate of children with CP plus more than 1 CCC diagnosis increased from 7.1 to 10.4 per 100 000 (P = .002), whereas the hospitalization rates of children with bronchopulmonary dysplasia plus more than 1 CCC diagnosis increased from 9.8 to 23.9 per 100 000 (P < .001). CONCLUSIONS: Consistent increases in hospitalization rates were noted among children with diagnoses in multiple CCC categories, whereas hospitalization rates of children with CP alone have remained stable. The relative medical complexity of hospitalized pediatric patients has increased over the past 15 years.

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Omphalocele, advanced maternal age, and fetal morbidity outcomes

Salihu

Emusu

Aliyu

et al. 2005

American J of Med Genetics Pt A

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In this study we wanted to determine if the risk for adverse neonatal outcome among omphalocele-affected fetuses is increased among older gravidas. This was a retrospective cohort study on live-born infants with omphalocele delivered in New York State from 1983 through 1999. We compared infants of older (>or=35 years) with those of younger (<35 years) mothers with respect to the following fetal morbidity indices: low birth weight and very low birth weight, preterm and very preterm, and small for gestational age. We used adjusted odds ratios to approximate relative risks. Data on a total of 1,010 infants with omphalocele were analyzed. Mean gestational age and birth weight were similar in both maternal age categories: mean+/-standard deviation (SD) for infants with omphalocele born to older mothers=37.4 weeks+/-3.9 versus 38.0 weeks+/-5.1 for those of younger mothers (P=0.2); mean birth weights+/-SD for infants with omphalocele born to older mothers=2,813+/-871.1 versus 2,958+/-809.9 for those of younger mothers (P=0.08). Also, the two maternal age sub-groups did not differ with respect to the fetal morbidity outcome: low birth weight (OR=0.95; 95% CI=0.60-1.51), very low birth weight (OR=0.78; 95% CI=0.36-1.69), preterm (OR=0.95; 95% CI=0.58-1.57), very preterm (OR=0.73; 95% CI=0.34-1.58), and SGA (OR=1.00; 95% CI=0.44-2.27). Thus, advanced maternal age does not appear to be a risk factor for fetal morbidity outcomes among omphalocele-affected fetuses. This information is potentially useful in counseling affected parents.

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Omphalocele and gastroschisis in the state of New York, 1992–1999

Abstract: Prevalence of gastroschisis has been on the rise while that of omphalocele has been declining in New York State. Geographical and racial/ethnic variations were observed, further confirming the notion of different etiologies for the two congenital anomalies.

Cited by 92 publications

References 35 publications

Maternal nativity as a risk factor for gastroschisis: A population‐based study

Maternal nativity as a risk factor for gastroschisis: A population‐based study

Increasing Prevalence of Medically Complex Children in US Hospitals

Omphalocele, advanced maternal age, and fetal morbidity outcomes

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