Suppose G is a finite group. The set of all centralizers of 2−element subsets of G is denoted by 2where Z(G) denotes the center of G. The aim of this paper is to present the main properties of (2, n)−centralizer groups among them a characterization of (2, n)−centralizer and primitive (2, n)−centralizer groups, n ≤ 9, are given.