Setup time is the amount of time required for a machine to adjust its settings or the preparation of a device at each stage to process and deliver a completed job. A novel approach for the n-job 2-machine generalized intuitionistic fuzzy flow shop scheduling problem, subject to the setup time, was proposed. When the machines are kept in different places, the transporting and return times of transport play a significant role in the production. Generalized triangular intuitionistic fuzzy numbers were considered to represent the processing, setup, transportation, and return times. This study aims to minimize the intuitionistic fuzzy total production time with less vagueness.