On aspiration biopsy of the liver, with remarks on its diagnostic significance.¹

Renal biopsy: Still a landmark for the nephrologist

“…The PRB was born in 1944 when Nils Alwall adapted a technique for percutaneous liver biopsy in the kidney, using an aspiration needle technique [4] with a radiographic procedure for the localization of the right kidney and keeping the patient in a sitting position. With this in novative method, he obtained adequate tissue in ten of the thirteen patients [5] .…”

Tru‐cut and Menghini needles: different yield in the histological diagnosis of liver disease

“…Cirrhosis was diagnosed only if proliferation of fibrous tissue and conversion of normal liver architecture into structurally abnormal nodules were observed (9). More subtle criteria for diagnosis were excluded.…”

“…More subtle criteria for diagnosis were excluded. It was also classified as macronodular (the majority of the nodules having a diameter greater than 3 mm), micronodular (the majority of the nodules having a diameter less than 3 mm), or mixed (9). The intensity of inflammation was evaluated using a scale of 0 to 3, as well as considering its location as either portal or periportal.…”

“…The study of liver disease has seen notable advances during the past 40 years thanks to the widespread use of percutaneous hepatic biopsy, a technique developed by Iversen & Roholm in 1939 (1).…”

The Variation of Pathological Changes in the Liver Evaluated by Double Biopsies

“…Since 1939. when Iversen & Roholm (8) and Baron (I) introduced needle biopsy as a diagnostic tool valuable in liver disease, much information has been obtained about different patho-anatomical conditions. This has been carefully described in the literature.…”