Let A be a non-commutative prime ring with involution *, of characteristic ≠2(and3), with Z as the center of A and Π a mapping Π:A→A such that [Π(x),x]∈Z for all (skew) symmetric elements x∈A. If Π is a non-zero CE-Jordan derivation of A, then A satisfies s4, the standard polynomial of degree 4. If Π is a non-zero CE-Jordan *-derivation of A, then A satisfies s4 or Π(y)=λ(y−y*) for all y∈A, and some λ∈C, the extended centroid of A. Furthermore, we give an example to demonstrate the importance of the restrictions put on the assumptions of our results.