On-demand preparation of calcium alginate microspheres via piezoelectric microfluidics

Li, Kai; Sun, Jianhua; He, Shaopeng; Zhou, Xianxin; Li, Hengyu; Liu, Yingxiang

doi:10.1016/j.sna.2022.113925

Cited by 10 publications

(6 citation statements)

References 33 publications

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“…where the ρ is the density of the viscous fluid used, ρ = 0.96 g/cm 3 , g is the acceleration of gravity, g = 980 cm/s 2 , and h is the height of the liquid column in the capillary rod.…”

Section: Performance Controllingmentioning

confidence: 99%

“…Piezoelectric microjet is a kind of micro-droplet injection technology based on piezoelectric drive, through which fluid is ejected into tiny droplets, and droplets can be ejected on demand [1,2]. It has outstanding advantages such as high injection precision, fast response speed, high efficiency, and a wide range of injection materials [3,4], and has been widely used in many industrial fields, such as microelectronic manufacturing [5], medical [6], chemistry [7], biology [6,8], space bearing lubrication [9], underwater drive [10], microfluid filtration [11], additive manufacturing [12][13][14], etc.…”

Section: Introductionmentioning

confidence: 99%

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Research on Self-Priming Piezoelectric Microjet and Its Ejection Performance Control

Shan

Zhou³

et al. 2023

Actuators

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The inkjet printing technology, based on piezoelectric microjet, realizes the high-efficiency processing of special-shaped structures, and has the advantages of high precision, high efficiency, and the ability to manufacture arbitrary complex parts. In this paper, a self-priming piezoelectric micro-jet device is proposed and its structure and microjet process are described. ANSYS two-phase two-way fluid-structure coupling simulation analysis is carried out, and the mechanism of the piezoelectric microjet is described in detail. The effects of voltage amplitude, input signal frequency, nozzle diameter, and oil viscosity on the ejection performance of the device are studied, and a set of effective control methods are summarized. Finally, the correctness of the piezoelectric microjet mechanism and the feasibility of the proposed self-priming piezoelectric micro-jet device are verified by experiments, and its ejection performance is tested. The experimental results are consistent with the ANSYS simulation results, which verifies the correctness of the experiment.

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“…where the ρ is the density of the viscous fluid used, ρ = 0.96 g/cm 3 , g is the acceleration of gravity, g = 980 cm/s 2 , and h is the height of the liquid column in the capillary rod.…”

Section: Performance Controllingmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Research on Self-Priming Piezoelectric Microjet and Its Ejection Performance Control

Shan

Zhou³

et al. 2023

Actuators

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show abstract

“…It has received extensive attention in the aspects of on-chip laboratory, chemical analysis, drug injection, inkjet printing, engine oil supply, electronic chip cooling process, and precision hydraulic work table [3][4][5][6][7][8][9].…”

Section: Introductionmentioning

confidence: 99%

A phase modulation method of sine signal for dual-active-valve piezoelectric pump

Sun,

Deng,

Wang

et al. 2024

Meas. Sci. Technol.

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A phase modulation method with wide range and high resolution for sine signal is essential for a dual-active-valve piezoelectric pump (DAVPP) control. In DAVPP, by phase modulation, the flow direction can be changed, the output flow rate and pressure can be precisely adjusted. In this article, the authors developed a phase modulation method for sine signal. This method is characterized by both the combination of hardware and software, and the combination of digital circuit and analog circuit. In hardware, a sinxcosφ constructing circuit and a cosxsinφ constructing circuit are specially structured, which enables phase modulation to be achieved. In software, the output phase is determined by the digital controlling quantities sent by the main control chip and stored in the form of a table. Analytical formulas of the cosine constructing table tab_cos and the sine constructing table tab_sin are analyzed and structured. Experimental results show that the output phase can be regulated linearly and continuously, within a range of 0° to 360°. Its resolution can be improved according to the requirements. Although the modulation process and circuit are simple, it can effectively solve the problem of sine signal phase modulation for DAVPP control.

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“…They can quickly switch between different operating states and achieve instantaneous fluid control. This characteristic is crucial in applications requiring rapid response and real-time adjustment, with broad prospects in microfluidic transport fields such as medical microinfusion [ 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 ], fuel cells [ 19 , 20 , 21 , 22 , 23 , 24 ], cooling systems [ 25 , 26 , 27 , 28 , 29 ], micromanipulation [ 30 , 31 ], and surface coating of fan blades [ 32 ]. In recent decades, researchers have extensively studied piezoelectric pumps and incorporated them into their products.…”

Section: Introductionmentioning

confidence: 99%

“…Meanwhile, the pump performance among the different convergence bending tubes decreases with the increase in curvature radius, which is consistent with the results of the simulations.Table4shows the forward and reverse flow resistance coefficients calculated from the simulation data. Figure16compares the experimental flow rates with the calculated theoretical flow rates by substituting the simulated flow resistances into Equation(12). Under the conditions of 100 V and 23 Hz, the maximum theoretical flow rate is 13.98 mL/min, whereas the maximum experimental flow rate is 5.69 mL/min.…”

mentioning

confidence: 99%

Design and Analysis of a Cardioid Flow Tube Valveless Piezoelectric Pump for Medical Applications

Wang,

Zhang,

Gui

et al. 2023

Sensors

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Piezoelectric pumps play an important role in modern medical technology. To improve the flow rate of valveless piezoelectric pumps with flow tube structures and promote the miniaturization and integration of their designs, a cardioid flow tube valveless piezoelectric pump (CFTVPP) is proposed in this study. The symmetric dual-bend tube design of CFTVPP holds great potential in applications such as fluid mixing and heat dissipation systems. The structure and working principle of the CFTVPP are analyzed, and flow resistance and velocity equations are established. Furthermore, the flow characteristics of the cardioid flow tube (CFT) are investigated through computational fluid dynamics, and the output performance of valveless piezoelectric pumps with different bend radii is studied. Experimental results demonstrate that CFTVPP exhibits the pumping effect, with a maximum vibration amplitude of 182.5 μm (at 22 Hz, 100 V) and a maximum output flow rate of 5.69 mL/min (at 25 Hz, 100 V). The results indicate that a smaller bend radius of the converging bend leads to a higher output flow rate, while the performance of valveless piezoelectric pumps with different diverging bends shows insignificant differences. The CFTVPP offers advantages such as a high output flow rate, low cost, small size for easy integration, and ease of manufacturing.

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On-demand preparation of calcium alginate microspheres via piezoelectric microfluidics

Cited by 10 publications

References 33 publications

Research on Self-Priming Piezoelectric Microjet and Its Ejection Performance Control

Research on Self-Priming Piezoelectric Microjet and Its Ejection Performance Control

A phase modulation method of sine signal for dual-active-valve piezoelectric pump

Design and Analysis of a Cardioid Flow Tube Valveless Piezoelectric Pump for Medical Applications

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