In this paper, the direct differentiation of generalized-α time integration is derived, equations are introduced and results are shown. Although generalized-α time integration has found usage, the derivation and the resulting equations for the analytical sensitivity analysis via direct differentiation are missing. Thus, here, the sensitivity equations of generalized-α time integration via direct differentiation are provided. Results with generalized-α are compared with Newmark-β time integration and their sensitivities with numerical sensitivities via forward finite differencing in terms of accuracy and performance. An example is shown for each linear structural dynamics and flexible multibody dynamics.