On-line SPE Using Ionic Liquid-Based Monolithic Column for the Determination of Antihypertensives in Human Plasma

The Influence of Ionic Liquids on the Effectiveness of Analytical Methods Used in the Monitoring of Human and Veterinary Pharmaceuticals in Biological and Environmental Samples—Trends and Perspectives

“…The developed SPE-HPLC-UV method offered the effective extraction of the analytes (93-105%), which allowed the target compounds to be quantified with LODs of 1-2 ng/mL. In a study by Liu et al [117] a poly(ionic liquid-glycidylmethacrylate-coethyleneglycol dimethacrylate) (IL-GMA-co-EDMA) monolithic column with 1-vinyl-3-butylimidazolium chloride ([ViC 4 MIM][Cl]) was synthesized and applied as an SPE sorbent in the on-line SPE-HPLC-UV method for the determination of nifedipine, nitrendipine and felodipine in human plasma samples. The best extraction of the analytes and purification of the matrix sample was obtained when a methanol/water mixture was used as the eluting agent.…”

Ionic liquids: solvents and sorbents in sample preparation

“…A vinylimidazolium-based IL was also used in the preparation of a monolithic sorbent for on-line SPE for biological samples. Liu et al employed a monolithic PIL column based on the 1-vinyl-3-butylimidazolium chloride ([VC 4 IM + ][Cl − ]) IL for the separation of three calcium antagonists [124]. The monolithic column was prepared using in situ polymerization between [VC 4 IM + ][Cl − ], glycidyl methacrylate, and ethylene dimethacrylate initiated by AIBN.…”

From Deep Eutectic Solvents to Nitrogen‐rich Ordered Mesoporous Carbons: A Powerful Host for the Immobilization of Palladium Nanoparticles in the Aerobic Oxidation of Alcohols

“…[64][65][66][67][68] Considering several advantageous characteristics of DESs over traditional ILs, such as higher degree of biodegradability and lower toxicity, and higher economic and environmental acceptability, they have been gradually becoming an excellent substitute for IL in many different chemical fields. [69][70][71][72][73][74][75][76][77][78] While traditional ionic liquids are widely used as carbon precursor in the field of synthesis of nitrogen-doped ordered mesoporous carbon materials, [7,64,[79][80][81][82][83] carbonization of DESs as appealing way to preparing these materials is still underdeveloped and to the best our knowledge there is no report on the synthesis and application of deep eutectic solvent derived ordered mesoporous carbons used as a support in chemical transformations. [84] If this approach could be realized in practice, it would a big step toward the development of environmentally sustainable processes for utilizing the functionalized carbon produced using different kinds of pyrolytic protocol in order to contribute to increasing the economic efficiency of the overall process.…”

“…These relatively cheap materials are a new class of ionic fluids which display physio‐chemical properties similar to those of the highly expensive common ionic liquids (ILs) [64–68] . Considering several advantageous characteristics of DESs over traditional ILs, such as higher degree of biodegradability and lower toxicity, and higher economic and environmental acceptability, they have been gradually becoming an excellent substitute for IL in many different chemical fields [69–78] . While traditional ionic liquids are widely used as carbon precursor in the field of synthesis of nitrogen‐doped ordered mesoporous carbon materials, [7,64,79–83] carbonization of DESs as appealing way to preparing these materials is still underdeveloped and to the best our knowledge there is no report on the synthesis and application of deep eutectic solvent derived ordered mesoporous carbons used as a support in chemical transformations [84] .…”