We construct a new bounded functional calculus for the generators of bounded semigroups on Hilbert spaces and generators of bounded holomorphic semigroups on Banach spaces. The calculus is a natural (and strict) extension of the classical Hille-Phillips functional calculus, and it is compatible with the other well-known functional calculi. It satisfies the standard properties of functional calculi, provides a unified and direct approach to a number of norm-estimates in the literature, and allows improvements of some of them. A ∋ f → f (A) := 1 2πi Γ f (λ)(λ − A) −1 dλ,