We consider a class of L 2 -supercritical inhomogeneous nonlinear Schrödinger equations with potential in three dimensionswhere 0 < b < 1 and α > 4−2b 3 . In the focusing case, by adapting an argument of Dodson-Murphy [14], we first study the energy scattering below the ground state for the equation with radially symmetric initial data. We then establish blow-up criteria for the equation whose proof is based on an argument of Du-Wu-Zhang [15]. In the defocusing case, we also prove the energy scattering for the equation with radially symmetric initial data.