2013
DOI: 10.1080/01621459.2013.806268
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On Optimal Designs for Nonlinear Models: A General and Efficient Algorithm

Abstract: Deriving optimal designs for nonlinear models is challenging in general. Although some recent results allow us to focus on a simple subclass of designs for most problems, deriving a specific optimal design mainly depends on algorithmic approaches. There is need of a general and efficient algorithm which is more broadly applicable than the current state of the art methods. We present a new algorithm that can be used to find optimal designs with respect to a broad class of optimality criteria, when the model par… Show more

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Cited by 93 publications
(132 citation statements)
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“…Other interesting aims are to extend the algorithm for several design variables and adjust it to multi-stage designs. The last point may be a difficult task since the multiplicative algorithm is only defined to one-stage designs (Yang [46]). …”
Section: Discussionmentioning
confidence: 99%
“…Other interesting aims are to extend the algorithm for several design variables and adjust it to multi-stage designs. The last point may be a difficult task since the multiplicative algorithm is only defined to one-stage designs (Yang [46]). …”
Section: Discussionmentioning
confidence: 99%
“…Several early versions were developed, including [30] and [28], and more recent and faster versions exist, such as [40] and [38]. The convergence properties of the original algorithm are analyzed in [21].…”
Section: Lemmamentioning
confidence: 99%
“…In contrast to the exact design framework where it is computationally prohibitive to do an exhaustive search over all possible designs to find a design that is globally optimal, the continuous design framework has well-established mathematical theories and tools to leverage for the fast identification of a globally optimal continuous design. In particular, we discuss in §3 the use of the general equivalence theorem (Kiefer 1974) and our extension of the optimal weight exchange algorithm by Yang et al (2013) to achieve this goal.…”
Section: Introductionmentioning
confidence: 99%
“…Based on the continuous design framework (see, for example, Silvey 1980, Pukelsheim 1993) and recent research on optimal designs in the statistics literature (Yang et al 2013), the proposed approach makes it computationally feasible to obtain heterogeneous designs with assured high design efficiency. We show through examples that compared to efficient heterogeneous choice designs obtained from the separate search approach recommended by Sándor and Wedel (2005), designs obtained through our proposed approach achieve efficiency gains from 12.5% to 16.6% (when measured by the D-error), and at the same time take only a fraction (12% to 20%) of the computation time.…”
Section: Introductionmentioning
confidence: 99%