On-site testing of sutured organs: An experimental set up to cyclically tighten sutures

Pascoletti, Giulia; Pressanto, Maria Chiara; Putame, Giovanni; Terzini, Mara; Audenino, Alberto; Zanetti, Elisabetta M.

doi:10.1016/j.jmbbm.2020.103803

Cited by 4 publications

(3 citation statements)

References 26 publications

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“…In the supplementary material, a video is provided where the application of the system to a laryngoplasty procedure is shown. Results obtained on 8 samples are reported extensively in other works by the same authors [ 1 , 6 ]: the system allowed obtaining consistent results (standard error below 12%) in spite of the natural variability among samples. In addition, in the same article, also ultimate load tests have been carried on with loads reaching 244 N.…”

Section: Experimental Testssupporting

confidence: 59%

Design of a loading system for cyclic test on sutured organs

et al. 2020

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The design of loading systems to test biologic samples is often challenging, due to shape variability and non-conventional loading set-ups. In addition to this, large economic investments would not be justified since the loading set up is usually designed for one single or for a limited range of applications. The object of this work is the development of a loading set-up finalised to on-site testing of sutures whose main function is applying a localised tensile load. The main challenges of this design process can be so summarized: Applying cyclic tensile loads on the suture wire, mimicking the physiologic condition where both suture anchorage points have a certain compliance; Designing a loading system as versatile as possible, in order to be able to accommodate organs with different geometries and sizes; Keeping low both the complexity and costs of realization. All these considerations and the design calculi are here reported in detail, discussing the novelty of the system, and its main advantages.

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Section: Experimental Testssupporting

confidence: 59%

Design of a loading system for cyclic test on sutured organs

et al. 2020

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“…All the constructs were mounted on a customized support, interfaced with a load testing machine (Instron Electropulse E300, Instron, Massachusetts) (Figure 2). A full description of the loading system is provided in a paper by Pascoletti et al 23 Briefly, the setup consists of a support base and a pulley system. The larynx was secured to the support base using adjustable bolts.…”

Section: Methodsmentioning

confidence: 99%

Ex vivo biomechanical evaluation of polyester and polyblend suture techniques to perform equine laryngoplasty

et al. 2022

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To validate the use of a polyblend tape suture in equine laryngoplasty (PL).Study design: Experimental study. Animals: Thirty-two cadaveric larynges.Methods: Each larynx was randomly assigned to 1 of 4 groups: PL with polyblend tape suture (TigerTape), without (TT) or with a cannula (TTC) in the muscular process of the arytenoid cartilage, and PL with polyester suture (Ethibond), without (EB) or with a cannula (EBC). Construct stiffness, total migration, creep, and drift values were measured after 3000 cycles. The specimens were then loaded to failure to assess their residual properties: load at failure, total energy, displacement, and 2 stiffness coefficients.Results: After cyclic testing, the total migration and creep were lower in TTC (6.36 ± 1.20 mm; 1.35 ± 0.38 mm/s) than in EB (11.12 ± 4.20 mm; 3.39 ± 2.68 mm/s) and in the TT constructs (11.26 ± 1.49 mm; 3.20 ± 0.54 mm/s); however, no difference was found with EBC (9.19 ± 3.18 mm; 2.14 ± 0.99). A correlation was found between total migration and creep (R = .85). The TTC constructs failed at higher loads (129.51 ± 33.84 N) than EB (93.16 ± 18.21 N) and EBC (81.72 ± 13.26 N) whereas the EB and EBC constructs were less stiff than TT and TTC (P < .001). Conclusion:Biomechanical properties were generally superior for the TTC constructs tested under cyclical loading. The TT and TTC constructs failed at a higher load than EB and EBC constructs. The cannula in TTC and EBC reduced the failure at the muscular process.Partial results of the study have been submitted and accepted as an oral communication at the 29th ECVS Congress, Valencia (Spain), 2-4 July 2020.

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“…Therefore, the implementation of a joint approach has permitted relevant steps forward in the understanding of various biomechanical aspects, thus permitting relevant improvements in the clinical sphere, such as in surgical or biomedical procedures [1][2][3][4][5], implants realisation [6][7][8][9][10][11][12] and prosthesis design [13][14][15][16][17]. On the one hand, experimental analysis provides further insights into materials characterisation at different scales [18][19][20][21][22][23][24][25][26], objectifies clinical qualitative outcomes [27][28][29][30][31][32][33][34][35] and lets numerical models be validated [36]. On the other hand, numerical studies allow studying wider test scenarios and inferring physical quantities otherwise tough to figure out because of feasibility and costs reasons [37][38][39][40][41][42][43][44][45]…”

Section: Introductionmentioning

confidence: 99%

Phantom -based lumbar spine experimental investigation and validation of a multibody model

Borrelli¹,

Formaggio²,

Civilini³

et al. 2021

Int. J. CMEM

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The study of the biomechanics of the human spine is not yet developed extensively. Recent developments in this field have heightened the need for observing the spine from a comprehensive perspective to understand the complex biomechanical patterns, which underlie the kinematic and dynamic responses of this multiple-joint column. Within this frame of exigence, a joint study embracing experimental tests and multibody modelling was designed. This study provides novel insights to the segmental contribution profiles in flexion and extension, analysing different forms of sagittal-plane angles. Moreover, the validation of the multibody model contributes to defining the key aspects for a consistent spine modelling as well as it introduces the basis for simulating pathological conditions and post-orthopaedic surgical outcomes.

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On-site testing of sutured organs: An experimental set up to cyclically tighten sutures

Cited by 4 publications

References 26 publications

Design of a loading system for cyclic test on sutured organs

Design of a loading system for cyclic test on sutured organs

Ex vivo biomechanical evaluation of polyester and polyblend suture techniques to perform equine laryngoplasty

Phantom -based lumbar spine experimental investigation and validation of a multibody model

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