Recently, some researchers have revisited the analysis of chlorine transportation in cylindrical pipes by deploying a coupling between the Laplace transform method and the complex analysis’ residue approach for inverting complex integrals. This method yielded interesting results after the incorporation of root-finding numerical schemes. Thus, away from incorporating numerical tools, the present study makes consideration of the same formulation of chlorine transport in a single-layered pipe and further extends it to the case of a bi-layered pipe using the hybrid of the Laplace transform method and the asymptotic approximations method. The need for asymptotic approximations for the modified Bessel functions, which arise in the reduced ordinary differential equations, necessitates the quest for closed-form analytical solutions, which are largely considered benchmark solutions for numerical investigations. Moreover, the obtained closed-form asymptotic solutions have been examined graphically; where it was observed that both the radial diffusion coefficient η and the spatial radial variable are contributory in the transport of chorine concentration in the media.