The aromatic compounds having structural configurations with two or more fused benzene rings are the polycyclic aromatic hydrocarbons(PAHs). Topological indices are valuable tools for studying the structure property relationships of PAHs and also helps in predicting various properties and activities. They find applications widely in computational chemistry, drug design and QSAR studies. This article focuses on analysing the potential predictive index for Sombor index( SO ), elliptic Sombor index(ESO ), Euler Sombor index(EU ), Reverse Sombor index(RSO), Reverse elliptic Sombor index(RESO ) and Reverse Euler Sombor index(REU ) using regression models for top priority 38 PAHs. From the study it is evident that, SO and RSO have proved to be potential predictive indices among the considered degree-based and reverse degree-based indices. The variation of best predictive index with minimal RMSE are plotted for linear, quadratic and cubic regression models for better understanding.