Many F class gas turbine combined cycle (GTCC) power plants are built in China at present because of less emission and high efficiency. It is of great interest to investigate the efficiency improvement of GTCC plant. A combined cycle with three-pressure reheat heat recovery steam generator (HRSG) is selected for study in this paper.In order to maximize the GTCC efficiency, the optimization of the HRSG operating parameters is performed. The operating parameters are determined by means of a thermodynamic analysis, i.e. the minimization of exergy losses. The influence of HRSG inlet gas temperature on the steam bottoming cycle efficiency is discussed. The result shows that increasing the HRSG inlet temperature has less improvement to steam cycle efficiency when it is over 590ºC. Partial gas to gas recuperation in the topping cycle is studied. Joining HRSG optimization with the use of gas to gas heat recuperation, the combined plant efficiency can rise up to 59.05% at base load. In addition, the part load performance of the GTCC power plant gets much better. The efficiency is increased by 2.11% at 75% load and by 4.17% at 50% load.