This review explores enhancing the reproductive performance and semen quality of sheep for optimal production and profitability. One element that has caught the attention of many researchers is selenium (Se), which plays a crucial biological role in improving reproductive efficiency, boosting antioxidant activity, enhancing semen characteristics, and supporting the immune system in both humans and animals. Se contains enzymes, such as glutathione peroxidase, which help to scavenge free radicals within cells and promote overall health. By incorporating Se into sheep management practices, farmers can potentially maximize their production and profitability while ensuring the health of their flocks. It's important to make sure that sheep have enough Se in their diet or by injection to prevent damage from free radicals and maintain their reproductive health. Supporting the antioxidant protection system is vital for this mineral, which helps counteract the harmful effects of these unstable molecules on cells. Ensuring that sheep have access to enough Se helps to maintain optimal semen quality and reproductive performance. It is noticeable that Se can synergize with vitamins and minerals to give good results in enhancing reproductive performance and semen quality. This review encompasses the studies that have been carried out to evaluate the beneficial impact of Se on sheep reproduction.