Flow in the wake of a blunt trailing edge profiled body, comprised of an elliptical leading edge and a rectangular trailing edge, has been investigated experimentally, to identify and characterize the secondary instabilities accompanying the von Kármán vortices. The experiments, which involve laser-induced fluorescence for visualization and particle image velocimetry for quantitative measurement of the wake instabilities, cover Reynolds numbers ranging from 250 to 2,150 based on thickness of the body, to include the wake transition regime. The dominant secondary instability appears as spanwise undulations in von Kármán vortices, which evolve into pairs of counterrotating vortices, with features resembling the instability mechanism predicted by Ryan et al. (J Fluid Mech 538:1-29, 2005). Feasibility of a flow control approach based on interaction with the secondary instability using a series of discrete trailing edge injectors has also been investigated. The control approach mitigates the adverse effects of vortex shedding in certain conditions, where it is able to amplify the secondary instability effectively.