The structural design of an eight-story building was examined to determine its performance in resisting ultimate loads. This was necessary for applying the building design in Indonesian regions with low to high seismic hazard levels. Studies have indicated that pushover analysis is suitable to assess the capacity of building structures against earthquake loads. However, as the structural design of each building produces its nominal strength, performance analysis must always be conducted. This study aimed at comparing the structural performance of buildings in regions with low, medium, and high seismic hazards, represented by the cities of Palembang, Jakarta, and Palu, respectively. A performance-based analysis was conducted using the pushover method to obtain the performance points. The responses of the building structures were the base shears, floor drifts, and inter-story drifts. The structural performance levels in the three regions were between immediate occupancy and life safety or were categorized as damage control, indicating minor damage. Because the structures exhibited high stiffness and ductility, they resisted the ultimate forces up to the damage control performance level in all regions. The greatest lateral drifts of 79.744 mm and 51.656 mm in the X- and Y-axis directions, respectively, occurred in Palu’s high seismic hazard region. The lowest lateral drift occurred in Palembang’s low seismic hazard region, in the X- and Y-axis directions of 59.401 mm and 38.378 mm, respectively.