1987
DOI: 10.1038/bjc.1987.16
|View full text |Cite
|
Sign up to set email alerts
|

On the age-dependent association between cancer of the breast and of the endometrium. A nationwide cohort study

Abstract: Summary The association between breast and endometrial cancer was investigated in a cohort consisting of 60,065 subjects (99% of all women in whom a first breast cancer was diagnosed in Sweden in 1960-63 and 1968-81 (Dunn, 1975;Cole & Cramer, 1977;Howe et al., 1984;Henderson et al., 1982;Willett & MacMahon, 1984). Descriptive epidemiologic studies have revealed high correlations between breast and endometrial cancer with regard to incidence and mortality rates. Such observations have been reported from inte… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

1
9
0

Year Published

1990
1990
2023
2023

Publication Types

Select...
8

Relationship

0
8

Authors

Journals

citations
Cited by 31 publications
(10 citation statements)
references
References 18 publications
1
9
0
Order By: Relevance
“…It is unclear as to why a stronger association between the E‐DII and EOC risk was observed mainly among older women. It is possible that these findings are consistent with the observation that environmental or lifestyle factors, such as the E‐DII, may be stronger determinants of hormonally sensitive cancers diagnosed in older women compared to cancers diagnosed in younger women, which are more genetically determined . In addition, our findings may reflect a cumulative effect of consumption of pro‐inflammatory foods over the life‐course.…”
Section: Discussionsupporting
confidence: 85%
See 1 more Smart Citation
“…It is unclear as to why a stronger association between the E‐DII and EOC risk was observed mainly among older women. It is possible that these findings are consistent with the observation that environmental or lifestyle factors, such as the E‐DII, may be stronger determinants of hormonally sensitive cancers diagnosed in older women compared to cancers diagnosed in younger women, which are more genetically determined . In addition, our findings may reflect a cumulative effect of consumption of pro‐inflammatory foods over the life‐course.…”
Section: Discussionsupporting
confidence: 85%
“…It is possible that these findings are consistent with the observation that environmental or lifestyle factors, such as the E-DII, may be stronger determinants of hormonally sensitive cancers diagnosed in older women compared to cancers diagnosed in younger women, which are more genetically determined. 41 In addition, our findings may reflect a cumulative effect of consumption of pro-inflammatory foods over the life-course. Another explanation could also be related to variations in insulin with aging as insulin resistance is associated with both older ages 42 and increases in inflammation.…”
Section: Cancer Epidemiologymentioning
confidence: 81%
“…Among non-tamoxifen patients, breast cancer and endometrial cancer naturally share common risk factors, such as obesity and high endogenous estrogen levels [50,51]. A Swedish national study [52] documented that breast cancer patients had a relative risk (RR) of 1.72 of developing a uterine malignancy. Furthermore this risk was agedependent and rose to 2.4 if the patient was above 70 years of age.…”
Section: Tamoxifen the Vagina And The Uterusmentioning
confidence: 99%
“…The relationship between different hormone-dependent tumors and the implications of hormone therapy as treatment for breast cancer or for other reasons (tamoxifen, THS, gonadotropins, etc.) make gynecologic follow-up obligatory (2,19,20). This is also necessary because uterine metastases may develop in patients with breast cancer.…”
Section: Discussionmentioning
confidence: 99%