On the Behavior of the Pyloric Sphincter in Normal Man

Mcclure, C. W.

doi:10.1001/archinte.1920.00100040033003

Cited by 33 publications

(2 citation statements)

References 7 publications

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“…The results obtained corresponded with those previously published (McClure et al, 1920;Baird et' al., 1924;Barsony and Egan, 1925;McCann, 1929). An easily opening pylorus still opened with ease after injection of acid, and the pylorus that opened with difficulty acted similarly after injection of the alkali.…”

Section: Experimental Findingssupporting

confidence: 93%

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Abolition of Pyloric Spasm by Orally Administered Procaine Solutions

Roka¹,

Lajtha²

1950

BMJ

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Section: Experimental Findingssupporting

confidence: 93%

“…Van Liere and Sleeth (1940) stated that increase of acidity increased motility, but this was denied by other authors (McClure et al, 1920;Baird, Campbell, and Hern, 1924;Bairsony and Egan, 1925;McCann, 1929).…”

mentioning

confidence: 99%

Abolition of Pyloric Spasm by Orally Administered Procaine Solutions

Roka¹,

Lajtha²

1950

BMJ

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New Methods for Estimating Enzymatic Activities of Duodenal Contents of Normal Man

Mcclure¹,

Wetmore²,

Reynolds³

1921

Arch Intern Med

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In a former paper 1 reference was made to the need of data concerning details of the physiology of the human gastrointestinal tract in order that experimental observations on the functional pathology of the latter might be more intelligently interpreted. The present communication is a continuation of physiologic investigation of the alimentary canal in normal man, and deals with methods for the study of the enzymatic activities of the duodenal contents. A r\l=e'\sum\l=e'\of most of the methods which have been used for such studies in the past is given in the appendix of the book of Euler.2 The methods, or their modifications, which have been used most frequently in investigation in clinical medicine are as follows: Proteolytic enzymes.\p=m-\Methods of Gross 3 and Mett.4 The method of Gross is a modification of one devised by Volhard.5 It is based on the principle that from faintly alkaline solutions (0.1 per cent, sodium carbonate) casein is precipitated by dilute acids (0.1 per cent. acetic acid), while the digestion products remain in solution. More recently this method was modified by Spencer.6 The Mett method is the well known one of measuring the lengths of coagulated egg albumin in capillary glass tubes before and after placing them into a solution of an enzyme. This method has been modified by Einhorn.7 Lipolytic enzyme.-Ethyl butyrate method. This method is based on the development of butyric acid by lipase and the determination of the acidity developed by titration with tenth normal sodium hydroxid.

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Motor Phenomena Occurring in Normal Stomachs, in the Presence of Peptic Ulcer and Its Pain, as Observed Fluoroscopically

Reynolds¹

1922

Arch Intern Med

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This communication embodies the principal results of fluoroscopic observations of the stomachs of normal men and of patients with ulcer of the stomach or duodenum, after the feeding a meal composed of meat and barium, which we have recently made. The ulcer patients were studied in order to obtain detailed information regarding gastric motor phenomena occurring throughout the period in which the stomach was emptying itself and during the occurrence of pain due to the presence of the ulcer; and, also, to attempt to establish an objective method for determining the effects of therapeutic measures. The normal patients were studied to obtain further data as to normal motor activity. It may seem that there is no need for further roentgen-ray observations on the motor activities of the normal human stomach, for considerable data 1 are available describing such observations after the ingestion of various kinds of solid foods. But clinicians and physiologists do not always seem to be cognizant of this fact as judged from statements found in current textbooks of medicine. For example, a recent leading system of medicine contains the statement, "then by means of onward circular constriction the material is pressed toward the pylorus, but the

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On the Behavior of the Pyloric Sphincter in Normal Man

Cited by 33 publications

References 7 publications

Abolition of Pyloric Spasm by Orally Administered Procaine Solutions

Abolition of Pyloric Spasm by Orally Administered Procaine Solutions

New Methods for Estimating Enzymatic Activities of Duodenal Contents of Normal Man

Motor Phenomena Occurring in Normal Stomachs, in the Presence of Peptic Ulcer and Its Pain, as Observed Fluoroscopically

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