On the biodegradation performance of an Mg–Y–RE alloy with various surface conditions in simulated body fluid

Hänzi, Anja C.; Gunde, Petra; Schinhammer, Michael; Uggowitzer, Peter J.

doi:10.1016/j.actbio.2008.07.034

Cited by 200 publications

(90 citation statements)

References 22 publications

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“…Thus, degradation of the introduced supporting structures made of magnesium alloys should be extended to this period. Roughness and density of the metallic surface are known to influence the corrosion rate in vivo [4][5][6][7][8][9]. Hence, in this study the influence of shot peening on roughness and load cycles of stabilizing structures based on the biodegradable magnesium alloys La2, LA63 and ZEK100 is assessed.…”

Section: Introductionmentioning

confidence: 99%

Influence of Shot Peening on Surface Roughness and Invitro Load Cycles of Magnesium Alloys

Bauer

Biskup

Schilling

et al. 2013

Biomedical Engineering / Biomedizinische Technik

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Surgical reconstruction of lesioned myocardium with vascularized bowel segments could provide a regenerative therapeutic approach. Because of the tissue's low load capacity shortly after surgery, a mechanical support of the biological graft with a stabilizing structure of magnesium alloy is necessary. In this study modification of surface roughness as a corrosion rate determining parameter by shot peening of stabilizing magnesium structures in vitro is assessed.

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Section: Introductionmentioning

confidence: 99%

Influence of Shot Peening on Surface Roughness and Invitro Load Cycles of Magnesium Alloys

Bauer

Biskup

Schilling

et al. 2013

Biomedical Engineering / Biomedizinische Technik

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“…It is known that the formation of OH -ions and gaseous hydrogen may be harmful to the life tissue 20 . Simultaneously considering the poor anti-corrosion properties, thus the bare magnesium alloys is not proper to used as biomedical materials.…”

Section: Resultsmentioning

confidence: 99%

Surface Properties Contrast between Al Films and TiO2 Films Coated on Magnesium Alloys by Magnetron Sputtering

Zhu

Chen

et al. 2017

Mat. Res.

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Al films and TiO 2 films were separately coated on AZ31 magnesium alloy substrates by means of magnetron sputtering method. The surface properties of the samples were explored and compared. Scanning electron microscope (SEM) observed the compact structure characteristics of as-deposited Al films and TiO 2 films. After heat treatment under 200ºC for half an hour the films kept the compact structure characteristics and there didn't exist structural defects on the surface of the films. Nano-indentation measurement results display that the micro-hardness of as-deposited Al film and TiO 2 film reaches about 1.90 Gpa and 1.51 Gpa, separately. Al film is a bit harder than TiO 2 film. Finally, the corrosion experiments in simulated body fluid initially indicate the different corrosion properties for Al film and TiO 2 film. Al film presents more effective anti-corrosion properties than TiO 2 film.

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“…The addition of rare earth metals has shown the most promise for improving the strength, but biocompatibility remains uncertain [9,43,48,49]. In addition, this strategy also does not lend itself well to tailor-ability.…”

Section: Discussionmentioning

confidence: 99%

A Strategy to Optimize Recovery in Orthopedic Sports Injuries

Sealy¹,

Liu²,

Li³

et al. 2017

J Bioanal Biomed

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An important goal for treatment of sports injuries is to have as short a recovery time as possible. The critical problem with current orthopedic implants is that they are designed to be permanent and have a high complication rate (15%) that often requires removal and replacement with a second surgery; and subsequently a second rehabilitation cycle. This study tests the feasibility of having a device that provides the needed mechanical properties, to promote healing for a specified amount of time and then degrades away to shorten recovery time. The specific strategy was to create a surface layer on a degradable metal alloy with a controllable degradation rate. Previous studies have shown the feasibility of using surface treatments to alter the surface integrity (i.e., topography, microhardness, and residual stress) leading to increased fatigue strength and a decreased degradation rate. This study was an extension of these previous studies to look at the changes in surface integrity and mechanical properties initially as well as the degradation over time for two surface treatments (shot peening and burnishing). Although the treatments improved initial properties and the burnishing treatment slowed the degradation rate, the faster degradation of the base material in vitro (compared to previous studies) probably reduced the overall impact. The study helped support the feasibility of this approach by showing the ability of the surface treatment to modify surface integrity, initial mechanical properties, and degradation rate; the degradation rate of the base material used needs to be slower and/or the surface treatment needs to create a bigger change in the degradation rate. Further it ultimately needs to be shown that the surface treatment can produce a material that will allow orthopedic devices to meet the required clinical design constraints in vivo.

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On the biodegradation performance of an Mg–Y–RE alloy with various surface conditions in simulated body fluid

Cited by 200 publications

References 22 publications

Influence of Shot Peening on Surface Roughness and Invitro Load Cycles of Magnesium Alloys

Influence of Shot Peening on Surface Roughness and Invitro Load Cycles of Magnesium Alloys

Surface Properties Contrast between Al Films and TiO2 Films Coated on Magnesium Alloys by Magnetron Sputtering

A Strategy to Optimize Recovery in Orthopedic Sports Injuries

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