In this paper we provide the basic setup for a project, initiated by Felix Rehren in [16], aiming at classifying all 2-generated primitive axial agebras of Monster type (α, β). We first revise Rehren's construction of an initial object in the cathegory of primitive n-generated axial algebras giving a formal one, filling some gaps and, though correcting some inaccuracies, confirm Rehren's results. Then we focus on 2-generated algebras which naturally part into three cases: the two critical cases α = 2β and α = 4β, and the generic case (i.e. all the rest). About these cases, which will be dealt in detail in subsequent papers, we give bounds on the dimensions (the generic case already treated by Rehen) and classify all 2-generated primitive axial algebras of Monster type (α, β) over Q(α, β) for α and β algebraically independent indeterminates over Q. Finally we restrict to the 2-generated Majorana algebras (i.e. when α = 1 4 and β = 1 32 ), showing that these fall precisely into the nine isomorphism types of the Norton-Sakuma algebras.