On the Complication Risk of Early Amniocentesis versus Standard Amniocentesis

Eiben, B.; Hammans, W.; Hansen, S; Trawicki, W.; Osthelder, B.; Stelzer, A; Jaspers, K.; Goebel, R

doi:10.1159/000264454

Cited by 32 publications

(19 citation statements)

References 10 publications

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“…However, should the sonogram fail to provide an explanation, the woman is generally offered amniocentesis-an invasive procedure that carries a small risk of miscarriage. 35 1996].) This risk, and the fact that most anomalies detected by fetal diagnosis have neither treatment nor cure, often leads pregnant women to experience intense anxiety if they screen AFP-positive.…”

Section: The Studymentioning

confidence: 99%

Strategies for Motivating Latino Couples' Participation in Qualitative Health Research and Their Effects on Sample Construction

2001

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Many investigators report difficulties recruiting low-income Latinos into health research projects, especially when they seek to enroll more than one family member. We developed a series of strategies that proved effective in motivating candidates who were initially reluctant to enroll. There is a possibility that these strategies biased the composition of the sample. Predictably, the reasons participants gave for enrolling were correlated with the recruitment strategy that had brought them into the study. Furthermore, we found statistically significant associations between recruitment technique and key study variables (e.g., the domestic stability of the couple). By increasing investigators' ability to recruit Latinos, however, the strategies outlined should help to ensure that Latinos' experiences are given due weight in the deliberations of medical professionals and policymakers.

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Section: The Studymentioning

confidence: 99%

Strategies for Motivating Latino Couples' Participation in Qualitative Health Research and Their Effects on Sample Construction

2001

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“…In two randomized studies [2,4], early amniocentesis was compared with standard amniocentesis at 15-16 gestational weeks. There was a significantly higher fetal loss rate after early amniocentesis in both studies.…”

Section: Introductionmentioning

confidence: 99%

Early Amniocentesis and Congenital Foot Deformities

et al. 2002

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Objective: Several studies have shown an increased risk of congenital foot derformities after early amniocentesis. These studies have comprised amniocenteses performed before 13 completed gestational weeks. In this study, the risk of foot deformities after amniocentesis performed at 12–14 completed gestational weeks was determined. Methods: 3,469 genetic amniocenteses in singleton pregnancies performed before 15 completed gestational weeks were studied. The intention was to perform the amniocenteses at 12–14 weeks of gestation, but 32 amniocenteses were performed at the gestational age 11 weeks + 5 days or 11 weeks + 6 days. The pregnancies were followed up with regard to fetal loss and leakage of amniotic fluid. After birth, newborns with a diagnosis of foot deformity were identified from the Swedish Medical Birth Registry. The observed number of foot deformities was then compared with the expected number which was calculated stratified for delivery hospital, year of birth, and maternal age. Results: The observed number of foot deformities was significantly higher than the expected: exact odds ratio 1.74 (exact 95% confidence interval 1.06–2.69). The rate of spontaneous abortions after the procedure was 1.8%, and the rate of leakage of amniotic fluid was 1.9%. There was a significant trend for all complications to decrease with increasing gestational age at amniocentesis. Conclusion: Women undergoing amniocentesis at 11+5 to 14+6 gestational weeks have an increased risk of giving birth to a child with a congenital foot deformity.

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“…Una década después de haber sido introducida, la AP es aún controversial en lo que se refiere a riesgos y morbididad fetal. Algunos estudios reportan mayor riesgo asociado al procedimiento (9-12) mientras otros destacan ser la AP segura y una alternativa a los otros métodos de colecta (13)(14)(15). En los trabajos publicados los resultados son influenciados por las características de la población y la metodología del procedimiento.…”

Section: Discussionunclassified