On the corrosion products of orthopedic implants

Cahoon, J. R.

doi:10.1002/jbm.820070409

Cited by 11 publications

(2 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These symptoms are an indication that the tissue is reacting to the implant. The corrosion of metallic implants can affect the surrounding tissues in three ways [38]: electrical currents may affect the behaviour of cells, the corrosion process may alter the chemical environment (pH, pO 2 ) and the metallic ions may affect cellular metabolism. Of the three, the last is usually the most severe.…”

Section: Corrosion Of Metallic Implant Materialsmentioning

confidence: 99%

Corrosion aspects of metallic implants — An overview

Balamurugan

Rajeswari

Balossier

et al. 2008

Materials & Corrosion

172

View full text Add to dashboard Cite

The ability to replace or augment diseased body parts totally or partially has improved both the quality and life span of human population. The decline in surgical risks during recent decades has encouraged the development of more complex procedures for prosthetic implantation. Additionally, a variety of extracorporeal devices, such as the heart, lung and blood dialysis machines are used routinely, but these prosthetic elements have several limitations. Hence, research projects are currently underway to overcome the limitations of synthetic materials by developing formulations with varying properties, such as asymptomatic, longterm function in the human physiological environment, etc., to meet the needs of biomedical surgeons. This review focuses on the several biomaterials corrosion and its measures to prevent corrosion.

show abstract

Section: Corrosion Of Metallic Implant Materialsmentioning

confidence: 99%

Corrosion aspects of metallic implants — An overview

Balamurugan

Rajeswari

Balossier

et al. 2008

Materials & Corrosion

172

View full text Add to dashboard Cite

show abstract

“…This results from an order-of-magnitude greater metal stiffness (or Young's modulus) relative to cortical (hard) bone and up to two orders of magnitude for cancellous (or trabecular), soft bone [1–3]. Wear debris production for contacting surfaces and the elimination of necessary vascularization are also often attendant issues [4]. However, the presence of a nonporous, stable passive film (TiO 2 ) on the surface minimizes the diffusion of metal ions from the bulk material and prevents corrosion of the material in contact with human tissues [2].…”

Section: Introductionmentioning

confidence: 99%

Next Generation Orthopaedic Implants by Additive Manufacturing Using Electron Beam Melting

Murr

Gaytan

Martínez

et al. 2012

International Journal of Biomaterials

259

121

View full text Add to dashboard Cite

This paper presents some examples of knee and hip implant components containing porous structures and fabricated in monolithic forms utilizing electron beam melting (EBM). In addition, utilizing stiffness or relative stiffness versus relative density design plots for open-cellular structures (mesh and foam components) of Ti-6Al-4V and Co-29Cr-6Mo alloy fabricated by EBM, it is demonstrated that stiffness-compatible implants can be fabricated for optimal stress shielding for bone regimes as well as bone cell ingrowth. Implications for the fabrication of patient-specific, monolithic, multifunctional orthopaedic implants using EBM are described along with microstructures and mechanical properties characteristic of both Ti-6Al-4V and Co-29Cr-6Mo alloy prototypes, including both solid and open-cellular prototypes manufactured by additive manufacturing (AM) using EBM.

show abstract

Growth inhibition of cultured fibroblasts by cobalt and nickel

Bearden

Cooke

1980

J. Biomed. Mater. Res.

View full text Add to dashboard Cite

It is known that tissues surrounding the site of an implanted prosthetic alloy are exposed to increased concentrations of the metals comprising the alloy. However, the exact identity and concentration of such metallic products are usually unknown, thus limiting the possibilities for quantifying any observed toxicological response to the metals. This report describes some of the effects of increased concentrations (7.5-30 microgram/ml; 1-5 x 10(-4)M) Of cobalt (as CoCl2.6H2O) and of nickel (NiCl2.6H2O) on the growth and morphology of cultured mouse fibroblasts. Ultrafiltration experiments indicated that much of the total Co or Ni present in cell culture medium could become bound to macromolecular serum components of the medium. Morphological changes and depressions in the cell growth rate were found to result from high concentrations (15-30 microgram/ml) of either Co or Ni. However, lower concentrations of nickel may have produced some stimulation of cell growth, whereas all concentrations of Co studied were found to depress the rate of cell growth. The growth rate of actively proliferating fibroblasts was quite sensitive to variations in the concentration of either cobalt or nickel. Increased concentrations of cobalt or nickel, therefore, might also affect the normal reconstructive activity of fibroblasts in vivo.

show abstract

On the corrosion products of orthopedic implants

Cited by 11 publications

References 6 publications

Corrosion aspects of metallic implants — An overview

Corrosion aspects of metallic implants — An overview

Next Generation Orthopaedic Implants by Additive Manufacturing Using Electron Beam Melting

Growth inhibition of cultured fibroblasts by cobalt and nickel

Contact Info

Product

Resources

About