On the design of Ag–morin nanocomposite to modify calcium alginate gel: framing out a novel sodium ion trap

Sarkar, Kangkana; Sen, Kamalika

doi:10.1039/c5ra10938h

Cited by 7 publications

(2 citation statements)

References 35 publications

(49 reference statements)

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“…It possesses multiple pharmacological applications, including anticancer, anti-inflammatory, antioxidant, antimicrobial, and anti-diabetic activities (Ghosh et al, 2016;Hwang-Bo et al, 2019;Salehi et al, 2019). The synthesis of colloidal AgNPs using morin through the liquid-phase route was reported previously (Sarkar & Sen, 2015;Terenteva et al, 2015). However, the major limitations of the liquidphase procedure are the low AgNPs yield and the use of a large amount of solvents (water and alcohols) during the preparation step.…”

Section: Introductionmentioning

confidence: 99%

Mass production of morin‐stabilized silver nanoparticles: Characterization, antioxidant, and antimicrobial activities

Zayed,

Abdel‐Monem,

Arafa

et al. 2023

Microscopy Res & Technique

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Phytochemical‐conjugated silver nanoparticles (AgNPs) are believed to act as a bridge between nanotechnology and therapy. There is a significant need for green and mass production of such materials due to their extensive applications, especially in the biomedical sector. In this study, morin‐stabilized silver nanoparticles (morin/AgNPs) were synthesized on a massive scale using a one‐pot solid‐state technique. The reaction is achieved by ball milling of morin and silver nitrate powders at ambient temperature without any solvent or toxic reagent. The prepared morin/AgNPs exhibited a semi‐hexagonal shape and ranged in size from 21 to 43 nm. The x‐ray diffraction results elucidated the formation of highly crystalline AgNPs. Fourier transform infrared and x‐ray photoelectron spectroscopic analyses prove that the hydroxyl, carbonyl, and aromatic functionalities in morin are playing major roles in the reduction and stabilization of AgNPs. The antioxidant potential of morin/AgNPs was evaluated utilizing 2,2‐Diphenyl‐1‐picryl‐hydrazyl (DPPH) assay. Morin/AgNPs exhibited better free radical scavenging activity (IC50 = 11.7 μg/mL) than morin (IC50 = 14.8 μg/mL). Furthermore, the synthesized AgNPs showed promising antimicrobial activity against Escherichia coli, Klebsiella pneumonia, Staphylococcus aureus, Streptococcus mutans, and Candida albicans. The largest inhibition zones were observed against S. aureus (21.2 ± 0.6 mm) and K. pneumonia (20.3 ± 0.5 mm) bacteria. The foregoing results highlighted the prospective application of morin/AgNPs as a promising antioxidant and antimicrobial material for safe medical applications.Research Highlights A simple green route for the large‐scale production of AgNPs was developed. Morin acts as reducing/stabilizing agent in solid‐state synthesis of AgNPs. Morin/AgNPs exhibited promising antimicrobial and antioxidant activity.

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Section: Introductionmentioning

confidence: 99%

Mass production of morin‐stabilized silver nanoparticles: Characterization, antioxidant, and antimicrobial activities

Zayed,

Abdel‐Monem,

Arafa

et al. 2023

Microscopy Res & Technique

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“…[ 1 ] Silver is a broad-spectrum antimicrobial for controlling a wide range of bacterial, fungal, and viral pathogens. [ 4 ] This manuscript will concentrate on the very newest of these dressings, Calgigraf Silver (Ag) foam with the following composition silver alginate, calcium alginate, and maltodextrin.…”

Section: Introductionmentioning

confidence: 99%

Efficacious use of a Calgigraf Ag foam dressing in complete healing of a difficult-to-heal, long-standing ulcer of osteoradionecrosis

Firdoose¹,

Hasoon

2018

Natl J Maxillofac Surg

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A number of dressings containing silver have been recently introduced into the wound care market as increased resistance to antibiotics has become a problem in treating infected wounds. A 54-year-old male, with adenoid cystic carcinoma treated by segmental resection and reconstruction of mandible using reconstruction plate with concomitant radiotherapy, resulted in a deep extraoral nonhealing necrotic, exuding, malodorous, and painful wound. Erythema, eczema, and trophic changes were surrounding the skin. Previous treatment was removal of exposed reconstruction plate and primary closure. Culture samples reported methicillin-resistant Staphylococcus aureus positive and sensitivity to linezolid. Repeated failed attempts to approximate the wound, prompted the use of Calgigraf Ag foam as dressing for the wound. Evidence of new tissue growth and subsequent reduction in wound area and exudate were significant. Chronic nonhealing wounds involving progressive tissue loss give rise to the biggest challenge to wound-care researchers. Despite proper care, some wounds fail to heal in normally and become chronic. The use of ionic silver with negative pressure therapy is safe and effective in difficult nonhealing wounds. This case illustrates the potential benefit of ionic silver combined with negative pressure and moist wound healing as management of a patient with long-standing, nonhealing, and osteoradionecrosis wound. Calgigraf Ag Foam a silver alginate dressing is optimal for maintaining moist environment vital to promote wound healing. It needs less frequent dressing changes with additional benefits such management of excessive exudate minimising malodour and maintaining a moist wound environment.

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Radiometric analysis of isotherms and thermodynamic parameters for cadmium(II) adsorption from aqueous medium by calcium alginate beads

Sarkar

Sen

Lahiri

2017

J Radioanal Nucl Chem

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On the design of Ag–morin nanocomposite to modify calcium alginate gel: framing out a novel sodium ion trap

Cited by 7 publications

References 35 publications

Mass production of morin‐stabilized silver nanoparticles: Characterization, antioxidant, and antimicrobial activities

Mass production of morin‐stabilized silver nanoparticles: Characterization, antioxidant, and antimicrobial activities

Efficacious use of a Calgigraf Ag foam dressing in complete healing of a difficult-to-heal, long-standing ulcer of osteoradionecrosis

Radiometric analysis of isotherms and thermodynamic parameters for cadmium(II) adsorption from aqueous medium by calcium alginate beads

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