Abstract-Notoriously, energy-efficient MAC protocols cause high latency of packets. Such delays may well increase when a routing protocol is applied. Therefore, quantifying the endto-end delay and energy consumption when low duty cycle MAC and routing protocols are jointly used, is of particular interest. In this paper, we present a comprehensive evaluation of the MERLIN (MAC and Efficient Routing integrated with support for localization) protocol. MERLIN integrates MAC and routing features into a single architecture. In contrast to many sensor network protocols, it employs a multicast upstream and multicast downstream approach to relaying packets to and from the gateway. Simultaneous reception and transmission errors are notified by using asynchronous burst ACK and negative burst ACK. A division of the network into timezones, together with an appropriate scheduling policy, enables the routing of packets to the closest gateway. An evaluation of MERLIN has been conducted through simulation, against both the SMAC and the ESR routing protocols,which is an improved version of the DSR algorithm. The results illustrate how both SMAC and ESR, jointly used in low duty cycle scenarios, can cause an impractical and very high end-to-end delays. MERLIN, as an integrated approach, notably reduces the latency, resulting in nodes that can operate in a very low duty cycle. Consequently, an extension of the operative lifetime of the sensor network is achieved.