Abstract.We have determined the irregular primes below 12 5000 and tabulated their distribution. Two primes of index five of irregularity were found, namely 78233 and 94693. Fermat's Last Theorem has been verified for all exponents up to 125000. We computed the cyclotomic invariants u \ v , and found that u" = 0 for all p < 12 5000. The complete factorizations of the numerators of the Bernoulli numbers B2k for 2k « 60 and of the Euler numbers E2k for 2k < 42 are given.