This report shortly reviews recent developments in fabrication and application of low-cost and low-volume microfluidic devices using fibrous structures, e.g individual fiber, threads, and textile fabrics. Microfluidic concept is capable via wicking (capillary action) either external pumping of fluids through pathways of multifilament threads and textile structure. Furthermore, textile patterning and combination of hydrophilic and hydrophobic fibrous materials can be helpful. Different materials, e.g. cotton fibers and hollow fibers, have been used by several techniques to form hydrophilic-hydrophobic contrast and liquid control in textile-based microfluidic devices. The wicking property and flexibility of fibrous structures make it suitable for 3D microfluidic devices.These fiber-based microfluidic systems have potential applications in diagnostics and human health monitoring systems.