Various physical, ecological, economic, etc phenomena are governed by planar differential systems. Sub- sequently, several research studies are interested in the study of limit cycles because of their interest in the understanding of these systems. The aim of this paper is to investigate a class of quintic Kolmogorov systems, namely systems of the form x=xP4 (x;y); y= y Q4 (x; y) ; where P4 and Q4 are quartic polynomials. Within this class, our attention is restricted to study the limit cycle in the realistic quadrant {(x; y) 2 R2; x > 0; y > 0}. According to the hypothesises, the existence of algebraic or non-algebraic limit cycle is proved. Furthermore, this limit cycle is explicitly given in polar coordinates. Some examples are presented in order to illustrate the applicability of our result