“…However, one cannot be successful without a deeper understanding of the dependencies: the feature values depend both on parameter choices during calculations, 7 but also on the parameters of the MR pulse-sequence. 8,9 Based on this understanding, we can define features that are robust with respect to the dependencies. 10 To further facilitate the data-driven approach, although challenging, it is crucial to create large and curated databases that also include a large span of the underlying dependencies.…”