Relevance. In order to optimize the methods of protecting the plant from the harmful organisms of hemp sowing, it seems significant to assess the effectiveness of modern pesticides and their effect on the physiological processes of plants.Methods. Studies were conducted on a variety of monoecious hemp of the Central Russian ecotype Nadezhda. The obtained results were analyzed in accordance with methodological recommendations for registration tests of fungicides and insecticides, methodological guidelines for conducting field and vegetation experiments with hemp.Results. Studies were carried out during 2020-2021 at the experimental field of the Federal Research Center for Bast Fiber Crops the Penza region. The data is presented to assess the influence of insecticidal and fungicidal protectors and spraying hemp insecticide sowing to reduce plant damage to harmful organisms, for morphometric indicators and economic signs. The greatest protective effect of the damage to the hemp flelling was obtained when using tribers of Tabu, VSK + Bunker, VSK on the background of spraying plants insecticide Samurai Super, CE 65%, from the prevalence of root rot. A significant impact on the morphometric indicators ensured the drying with the preparations of Selest Top, CS and Tabu, VSK on the background of spraying by insecticide, as well as the use of them in a combination with a Benorad, WP. Against the background of spraying plants insecticide installed a reliable increase in the control of the yield of stems when processing seed preparations Selest Top, CS + Benorad, WP (2.1 t/ha), seed yields — when using preparations Selest Top, CS + Bunker, VSK (0,13 t/ha); Tabu, VSK + Benorad, WP and Bunker, VSK (0.15 and 0.24 t/ha), on the collection of fibers — when using Tabu, VSK + Bunker, VSK (0.63 t/ha), to collect oil — when drancing the preparations of Selest Top, CS + Bunker, VSK (0.04 t/ha); Tabu, VSK + Benorad, WP and Bunker, VSK (0.05 and 0.08 t/ha).