On the interference of sildenafil on platelet aggregation: An ex vivo pilot study

Coagulopathy: A Possible Mechanism of Terlipressin-induced Peripheral Ischemic Complications – Evidence from Published Case Reports

“…[1] Again, both alprostadil and sildenafil have strong antiplatelet action. [15,16] Hence, antiplatelet action of these agents may be responsible for the improvement of cutaneous lesions. Hence, to conclude, "coagulopathy" along with "vasoconstriction" seems to be the most likely mechanism of terlipressin-induced ischemic complications [the possible mechanism is shown in evidence.…”