1953
DOI: 10.3891/acta.chem.scand.07-1170
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On the Intracellular Distribution of Catalase and Alcohol Dehydrogenase in Horse, Guinea Pig and Rat Liver Tissues.

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Cited by 68 publications
(8 citation statements)
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“…The observation that oxygen consumption does not change significantly when ethanol infusion is started, taken along with the finding that the ATP concentration of liver is not diminished by ethanol administration (27), sheds some light on the question of oxidative phosphorylation from extramitochondrial DPNH. The alcohol dehydrogenase responsible for the oxidation of ethanol is known to be exclusively present in the cytoplasm (31). It is therefore suggested that the yield of high energy bonds from DPNH is the same whether the DPNH is formed inside the mitochondria or not.…”
Section: Methodsmentioning
confidence: 98%
“…The observation that oxygen consumption does not change significantly when ethanol infusion is started, taken along with the finding that the ATP concentration of liver is not diminished by ethanol administration (27), sheds some light on the question of oxidative phosphorylation from extramitochondrial DPNH. The alcohol dehydrogenase responsible for the oxidation of ethanol is known to be exclusively present in the cytoplasm (31). It is therefore suggested that the yield of high energy bonds from DPNH is the same whether the DPNH is formed inside the mitochondria or not.…”
Section: Methodsmentioning
confidence: 98%
“…In biochemical studies, Nyberg et al (22) showed that most of the ADH activity in horse and rat liver is found in the cytosol. Lieber and DeCarli (14) reported that the ADH activity in rat liver is found in the cytosol, but not in either the mitochondrial or the microsomal fractions.…”
Section: Discussionmentioning
confidence: 99%
“…Our major improvement in the method of Alvarez and Furshpan has been the selection of a class of dye with exteremly favorable properties. The results we present are selected to indicate the potentialities of the method, which we believe will have general applicability in studies where a knowledge of cellular geometry is important (4).…”
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confidence: 99%