On the maintenance of the polymorphism at the ref(2)P locus in populations of Drosophila melanogaster

Fleuriet, Annie; Vazeille, Marie

doi:10.1007/bf00056542

Cited by 5 publications

(5 citation statements)

References 16 publications

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“…These findings are consistent with other Drosophila studies (Fleuriet and Vageille 1982;Cadieu 1983;Barnes 1984;Rose 1984;Hercus and Hoffmann 2000), which showed a maternal age effect on offspring viability. In a recent study on Drosophila serrata (Hercus and Hoffmann 2000), offspring viability began to decline with maternal age from the first day of oviposition, and the decline was approximately linear.…”

Section: Parental Age and Offspring Viabilitysupporting

confidence: 93%

“…As it has now been demonstrated in a number of independent studies (this study, Fleuriet and Vageille 1982;Cadieu 1983;Barnes 1984;Rose 1984;Kerver and Rotman 1987), there seems to be little ground to doubt that a decline in offspring viability is a typical feature of Drosophila melanogaster. A similar pattern has been discovered in several other arthropod systems (Fox 1993;Mohaghegh et al 1998;reviewed by Fox and Czesak 2000) and in yeast (Kennedy et al 1994).…”

Section: Offspring Quality and The Evolutionary Theory Of Agingmentioning

confidence: 65%

“…Because parental effects often reflect variation in parental condition, it is conceivable that older, senescent parents produce offspring of lower quality, i.e., of lower probability of survival or slower growth rate. A decline in offspring viability or developmental rate with maternal age has indeed been observed in Drosophila melanogaster (Fleuriet and Vageille 1982;Cadieu 1983;Barnes 1984;Rose 1984;Kerver and Rotman 1987), D. serrata (Hercus and Hoffmann 2000), and some other species (Fox 1993;Kennedy et al 1994;Mohaghegh et al 1998;Fox and Czesak 2000). This could be seen as a mechanistic consequence of the general decline in maternal performance due to senescence.…”

mentioning

confidence: 90%

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Decline in Offspring Viability as a Manifestation of Aging in Drosophila Melanogaster

et al. 2001

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Abstract. The evolutionary explanation of senescence proposes that selection against alleles with deleterious effects manifested only late in life is weak because most individuals die earlier for extrinsic reasons. This argument also applies to alleles whose deleterious effects are nongenetically transmitted from mother to progeny, that is, that affect the performance of progeny produced at late ages rather than of the aging individuals themselves. We studied the effect of maternal age on offspring viability (egg hatching success and larva-to-adult survival) in two sets of Drosophila melanogaster lines (HAM/LAM and YOUNG/OLD), originating from two long-term selection experiments. In each set, some lines (HAM and YOUNG, respectively) have been selected for early reproduction, whereas later reproduction was favored in their counterparts (LAM and OLD). In the HAM and LAM lines, both egg hatching success and larval viability declined with mother's age and did so with accelerating rates. The hatching success declined significantly faster with maternal age in HAM than in LAM lines, according to one of two statistical approaches used. Egg hatching success also declined with maternal age in YOUNG and OLD lines, with no difference between the selection regimes. However, the relationship between mother's age and offspring larva-to-adult viability differed significantly between these two selection regimes: a decline of larval viability with maternal age occurred in YOUNG lines but not in OLD lines. This suggests that the rate with which offspring viability declines with mother's age responded to selection for early versus late reproduction. We suggest broadening the evolutionary concept of senescence to include intrinsically caused declines in offspring quality with maternal age.

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Section: Parental Age and Offspring Viabilitysupporting

confidence: 93%

Section: Offspring Quality and The Evolutionary Theory Of Agingmentioning

confidence: 65%

mentioning

confidence: 90%

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Decline in Offspring Viability as a Manifestation of Aging in Drosophila Melanogaster

et al. 2001

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“…Its action upon the virus would be a secondary effect, to which the virus had had to become adapted. One of the selective components working on this locus would act during larval stages (Fleuriet & Vazeille, 1982).…”

Section: P -0 Polymorphismmentioning

confidence: 99%

Perpetuation of the hereditary sigma virus in populations of its host, Drosophila melanogaster. Geographical analysis of correlated polymorphisms

Fleuriet¹

1986

Genetica

Self Cite

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In natural populations of Drosophila melanogaster, about 10070 of the individuals are infected by a virus, sigma, which is not contagious but is transmitted through gametes. These populations are also regularly polymorphic for two alleles, O and P, of a locus ref(2)P; the P allele interferes with the multiplication of the virus. Two viral Types are found in populations, differing in their sensitivity to the P allele. Many samples of flies have been collected in different parts of the world and for each of them, the P frequency has been measured and the viral Type determined. A clear geographical differentiation appears for both these traits; they present a mutual adaptation leading to relatively low frequencies of infected flies in natural populations. Most viruses are only known from highly selected laboratory strains. The observations reported in this paper give evidence of the self restraint exercised by the sigma virus at the population level; they indicate that the characteristics of wild viral clones are likely to differ from those of laboratory strains and also from one population to another.The sigma virus is comparable to other genetical elements, that can be more efficiently transmitted than a mendelian allele, such as transposable elements. The discussion illustrates some of the factors involved in the perpetuation of such elements in a population and points out the difficulty of taking them all into consideration in theoretical models dealing with their perpetuation.

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“…A decline in offspring viability or developmental rate with maternal age has indeed been observed in Drosophila melanogaster (Fleuriet and Vageille 1982;Cadieu 1983;Barnes 1984;Rose 1984;Kerver and Rotman 1987), D. serrata (Hercus and Hoffmann 2000), and some other species (Fox 1993;Kennedy et al 1994;Mohaghegh et al 1998;Fox and Czesak 2000). A decline in offspring viability or developmental rate with maternal age has indeed been observed in Drosophila melanogaster (Fleuriet and Vageille 1982;Cadieu 1983;Barnes 1984;Rose 1984;Kerver and Rotman 1987), D. serrata (Hercus and Hoffmann 2000), and some other species (Fox 1993;Kennedy et al 1994;Mohaghegh et al 1998;Fox and Czesak 2000).…”

mentioning

confidence: 91%

Decline in Offspring Viability as a Manifestation of Aging in Drosophila Melanogaster

Kern

Ackermann

Stearns

et al. 2001

Evol

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The evolutionary explanation of senescence proposes that selection against alleles with deleterious effects manifested only late in life is weak because most individuals die earlier for extrinsic reasons. This argument also applies to alleles whose deleterious effects are nongenetically transmitted from mother to progeny, that is, that affect the performance of progeny produced at late ages rather than of the aging individuals themselves. We studied the effect of maternal age on offspring viability (egg hatching success and larva‐to‐adult survival) in two sets of Drosophila melanogaster lines (HAM/LAM and YOUNG/OLD), originating from two long‐term selection experiments. In each set, some lines (HAM and YOUNG, respectively) have been selected for early reproduction, whereas later reproduction was favored in their counterparts (LAM and OLD). In the HAM and LAM lines, both egg hatching success and larval viability declined with mother's age and did so with accelerating rates. The hatching success declined significantly faster with maternal age in HAM than in LAM lines, according to one of two statistical approaches used. Egg hatching success also declined with maternal age in YOUNG and OLD lines, with no difference between the selection regimes. However, the relationship between mother's age and offspring larva‐to‐adult viability differed significantly between these two selection regimes: a decline of larval viability with maternal age occurred in YOUNG lines but not in OLD lines. This suggests that the rate with which offspring viability declines with mother's age responded to selection for early versus late reproduction. We suggest broadening the evolutionary concept of senescence to include intrinsically caused declines in offspring quality with maternal age.

show abstract

On the maintenance of the polymorphism at the ref(2)P locus in populations of Drosophila melanogaster

Cited by 5 publications

References 16 publications

Decline in Offspring Viability as a Manifestation of Aging in Drosophila Melanogaster

Decline in Offspring Viability as a Manifestation of Aging in Drosophila Melanogaster

Perpetuation of the hereditary sigma virus in populations of its host, Drosophila melanogaster. Geographical analysis of correlated polymorphisms

Decline in Offspring Viability as a Manifestation of Aging in Drosophila Melanogaster

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