On the possibility of carbamate-directed hydroboration. An approach to the asymmetric synthesis of 1-aminocyclopentane-1,3-dicarboxylic acid

Recent progress on the stereoselective synthesis of cyclic quaternary α-amino acids

“…In a similar way, (1 S ,3 R )- 256 was transformed into (1 S ,3 S )-ACPD 506 in 34% overall yield (Scheme 104). 207…”

The transition metal catalyzed hydroboration of enamines

“…A series of phenethylamines, important substructures in biologically relevant molecules such as dopamine, amphetamine, and adrenaline, have recently been prepared by the hydroboration of enamines using 9-BBN [39]. Although the amine-directed uncatalyzed hydroboration using H 3 BÁTHF is known [40,41], to the best of our knowledge, the metal catalyzed hydroboration of enamines has not yet been reported. While a number of different transition metals are known to catalyze hydroborations, reactions employing rhodium complexes are the most common.…”

An Efficient and Waste-Minimized One-Pot Procedure for the Preparation of N-Boc-γ-amino Alcohols Starting from α,β-Unsaturated Ketones in Flow

“…N-Boc-β-aminoketones 3a, 3b, 3c, 3d, 3e and 3g are new compounds while 3f is a known compound. 23 Characterization data are reported in the Electronic Supplementary Information (ESI).…”