Horizontal pneumatic conveying and fluidization are two important gas-solid flow operations employed in wide-ranging industries from agro-processing to pharmaceutical and oil and gas. Despite being employed in industry for decades, they are still largely run on rulesof-thumb and experience rather than scientific principles. This research effort endeavors to contribute to their physical understanding by analyzing the effects of particle properties and varying operating conditions on these phenomena. This thesis is divided into three parts focusing on horizontal pneumatic conveying, fluidization and reactor modeling respectively.Part I deals with the minimum pickup velocity (Upu), defined as the minimum gas velocity required to initiate motion of a particle initially at rest, a very important parameter in horizontal pneumatic conveying. In this section, firstly, the effect of continuous particle size distribution (PSD) and particle shape on Upu is studied, where the involvement of inter-particle momentum transfer and particle rotation and lift is revealed. Secondly, the effect of particle diameter, density and shape on Upu is studied by investigating binary mixtures. Thirdly, the Upu of nanoparticles is reported for the first time and behavioral differences between polar and apolar nanoparticles are noted. Finally, the knowledge gap in Upu at the nano-and micro-scales is bridged by investigating particles from diameters 5 nm to 110,000 nm and the Three-zone Model developed for the micro-scale is modified to incorporate nanoparticles.Part II discusses the minimum fluidization velocity (Umf), and differential pressure signals and radial mass flux distribution in circulating fluidized beds (CFBs). Specific studies include the following: (i) a comparative analysis of the predictions of over a hundred empirical correlations to determine Umf with respect to Geldart Groups A, B and D, and bed voidage and particle sphericity; and (ii) investigating the effects of particle properties, namely, particle diameter and density, and varying operating conditions, namely, superficial gas velocity and