On the Proliferation of the Squamous Epithelium on the Portio Vaginalis Uteri: A colposcopic, histologic and cytologic study

Acta Obstet Gynecol Scand

1982

The great majority of cervical neoplasia begin in the transformation zone between the squamous and the columnar epithelium, i.e. within the area in which metaplasia takes place. This process, both normal and atypical, can be studied colposcopically. Colposcopy increases the diagnostic accuracy and therapeutic success in cervical neoplasia as it is the only method that permits a topographical study of cervical lesions, and indicates the location of neoplastic epithelial proliferation.

Section: Methodsmentioning

confidence: 99%

“…In the present work an attempt was made to create a colposcopic classification of the process of transformation into three categories by evaluating histologically three vascular and two epithelial colposcopic definitions in the uterine cervix based on previous studied by Cartier (2), Koller (9, Kolstad (6,7) and the present author (12).…”

Section: Category Bmentioning

confidence: 99%

Colposcopic Pattern of Cervicitis, Dysplasia and Previnvasive Cancer of the Uterine Cervix

Acta Obstet Gynecol Scand

1982

CO₂ laser vaporization for chronic cervicitis

1985

Lasers Surg Med

Chronic cervicitis is the most common disease occurring during the period of greatest sexual activity and reproductivity, and it is the most common gynecologic disease in young women. The disease is a common sequel to normal delivery and one of the main causes of infertility; it also may be precancerous. All the treated women in the present study exhibited preoperatively severe subjective symptoms for chronic cervicitis, and 32 out of 60 (53%) exhibited colposcopically atypical squamous epithelium. The women were examined 3, 6, and 12 months following laser surgery: 58 (97%) of them reported a decreasing intensity of their symptoms, and colposcopy revealed a normal postlaser transformation zone as well as a decreasing edema of cervical epithelium.

Koilocytotic Metaplasia and Intra‐epithelial Neoplasia of the Uterine Cervix

Acta Obstet Gynecol Scand

1984

It is emphasized that both metaplasia and CIN (cervical intra-epithelial neoplasia) must be defined with great precision in order to optimize an individualized treatment. In addition, if the metaplasia or CIN is classified as koilocytotic, the koilocytes must necessarily be found in the same cell layers as the metaplastic and/or the neoplastic cells. In a material of 335 unselected, consecutively treated women evaluated colposcopically, a marked difference between dysplasia (CIN 1 -2) and preinvasive cancer (CIN 3) was found cytologically and histologically, in that the incidence of koilocytotic atypia in CIN 3 lesions was only half of that in CIN 1 -2 lesions. The diagnostic accuracy of cervicovaginal cytology in koilocytotic metaplasia and koilocytotic CIN was poor: exfoliated koilocytotic cells were found in only 25% of the cases with histologically proven koilocytotic atypia, even when the cytological smears were reexamined. Furthermore, no characteristic colposcopic picture of koilocytotic metaplasia or CIN was found. It seems probable that koilocytotic dysplasia does not necessarily behave in the same way as classical CIN, which has been thought to progress continuously from mild dysplasia (CIN 1) to preinvasive cancer (CIN 3), since rapid progression of koilocytotic CIN 2 lesion directly into invasive cancer has been demonstrated. The C02-laser has been used to treat koilocytotic cervical intra-epithelial neoplasias. In 49 of the 52 cases so treated in this series, complete eradication of the disease was noted at two postoperative colposcopic and cytological examinations, 3 and 6 months after treatment, respectively.