This paper derives some refined versions of the Azuma-Hoeffding inequality for discrete-parameter martingales with uniformly bounded jumps, and it considers some of their potential applications in information theory and related topics. The first part of this paper derives these refined inequalities, followed by a discussion on their relations to some classical results in probability theory. It also considers a geometric interpretation of some of these inequalities, providing an insight on the interconnections between them. The second part exemplifies the use of these refined inequalities in the context of hypothesis testing and information theory, communication, and coding theory. The paper is concluded with a discussion on some directions for further research. This work is meant to stimulate the use of some refined versions of the Azuma-Hoeffding inequality in information-theoretic aspects.