“…The persistent increase in healthcare expenditure is a potential risk jeopardizing the sustainability of the healthcare system and its capacity to deliver affordable healthcare services to the public. The major determinants of healthcare expenditure growth identified by previous studies include population ageing [ 1 , 2 , 3 , 4 , 5 , 6 , 7 ], business cycles and income [ 2 , 3 , 6 , 8 , 9 , 10 , 11 , 12 ], technological innovation [ 1 , 2 , 11 , 13 , 14 , 15 ], and Baumol’s cost disease, a term used to describe the increase of healthcare price due to unbalanced growth of productivities between the healthcare sector and the whole economy [ 3 , 16 , 17 , 18 ]. It is crucial to point out that the network transmission mechanisms underlying these determinants effecting healthcare expenditure change come from the expansion or compression of morbidities resulting from demographic, socioeconomic, and environmental changes in the process of human development [ 19 , 20 ].…”