On the relationship between tibia torsional deformation and regional muscle contractions in habitual human exercises in vivo

Partial weight bearing of the tibia

“…The fact that GRFpk  foot usage interaction was revealed for torsion and less for AP-bending is well in line with our current understanding of in-vivo lower leg bone deformation [12,16]. Mediolateral Post.…”

“…1). Tibia deformation angles (bending and torsion) were calculated from the relative translation between markers in the same way as in our previous publications [12][13][14][15][16]. Matlab (The MathWorks, Inc.…”

“…In the literature, it has not yet been addressed whether, as one would expect on biomedical grounds, forefoot loading does actually lead to higher bone deformation than rear-foot loading, and to what extent this might be affected by PWB. We recently showed that the torsional deformation angle during both stair ascent and running was larger with forefoot strike than rear foot strike [12]. During isometric plantar flexion, tibia deformation regimes were characterized more by torsion than bending, which leads to the conclusion that tibia torsional deformation is closely related to calf muscle contractions.…”

“…Our group has recently developed a method that allows in vivo measurements of human bone deformation during exercise, called "optical segment tracking (OST)" [12][13][14][15][16]. Motion Capture is used to track markers mounted on screws that are mono-cortically inserted into the bone (e.g.…”

Preclinical testing of drug delivery systems to bone

“…This is mainly because of the body weight [29,30]. The mechanical loading is important during bone development and fracture healing.…”