Till now, kinetic theory and statistical mechanics of either free or interacting point particles were well defined only in non-relativistic inertial frames in the absence of the long-range inertial forces present in accelerated frames. As shown in the introductory review at the relativistic level, only a relativistic kinetic theory of "world-lines" in inertial frames was known till recently due to the problem of the elimination of the relative times. The recent Wigner-covariant formulation of relativistic classical and quantum mechanics of point particles required by the theory of relativistic bound states, with the elimination of the problem of relative times and with a clarification of the notion of the relativistic center of mass, allows one to give a definition of the distribution function of the relativistic micro-canonical ensemble in terms of the generators of the Poincaré algebra of a system of interacting particles both in inertial and in non-inertial rest frames. The non-relativistic limit allows one to get the ensemble in non-relativistic non-inertial frames. Assuming the existence of a relativistic Gibbs ensemble, also a "Lorentz-scalar micro-canonical temperature" can be defined. If the forces between the particles are short range in inertial frames, the notion of equilibrium can be extended from them to the non-inertial rest frames, and it is possible to go to the thermodynamic limit and to define a relativistic canonical temperature and a relativistic canonical ensemble. Finally, assuming that a Lorentz-scalar one-particle distribution function can be defined with a statistical average, an indication is given of which are the difficulties in solving the open problem of deriving the relativistic Boltzmann equation with the same methodology used in the non-relativistic case instead of postulating it as is usually done. There are also some comments on how it would be possible to have a hydrodynamical description of the relativistic kinetic theory of an isolated fluid in local equilibrium by means of an effective relativistic dissipative fluid described in the Wigner-covariant framework.