As intensive work is underway in leading material science centers in the USA, EU, Russia, and China, both to modernize existing titanium alloys and to create new ones, the E.O. Paton Electric Welding Institute of the National Academy of Sciences of Ukraine developed titanium alloys T110 (Ti-5.5Al-1.2Mo-1.2V-4Nb-2Fe-0.5Zr system) and T120 (Ti-6.5Al-3Mo-2.5V-4Nb-1Cr-1Fe-2.5Zr system), which according to their characteristics, belong to the group of modern two-phase high-alloyed alloys characterized by high strength and good ductility. With more and more attention is being paid to the expansion in the usage of welded structures and assemblies of high strength titanium alloys with UTS ≥ 1100 MPa, there’s urgent need in studying best ways to obtain welded joints from such alloys. The weldability of two-phase high-alloyed titanium alloys, the use of which can give big reduction in structural weight, is significantly worse than low-alloyed alloys, therefore for a new alloy it is necessary to ensure the possibility of obtaining welded joints with a strength of at least 90% compared to the strength of base material. The aim of this work is to study the influence of the welding thermal cycle and reducing of weld metal alloying degree on the structure and mechanical properties of welded joints of high-strength titanium alloy Ti-6.5Al-3Mo-2.5V-4Nb-1Cr-1Fe-2.5Zr with tensile strength more than 1200 MPa, as well as assessment of it welded joints properties in comparison with other high-strength titanium alloys.