On the supramolecular mechanism of cell-cell commutation

Abstract

Processes of cell commutation via anisometric supramolecular structures (strings) are considered in vitro and using physicochemical models of lipids and trifluoroacetylated amino alcohols. The biological effectiveness of commutation via strings is demonstrated to be higher compared to the diffusion mechanism of transfer of biologically active molecules over distances between objects typical of populations of microor ganisms. A kinetic model of strings is developed, and the rate of signal transmission in such systems is esti mated. It is shown that the condition of the chirality of lipids forming the biomembranes of cells follows from the experimentally observed cell commutation by means of supramolecular anisometric structures.

Hydrodynamic Engineering Approaches for Modeling of the Surface Cell Morphogenesis as Applications of Rosen's Optimality Theory

“…Since the strings along with branes -membranes in Mtheory are extended objects, it is possible to describe the formation of their analogs such as strings and membranous structures formed in biochemical systems [15]- [17] using Joukowski formula. However, as such systems possess the analogy with cell communication [18][19][20], it would be useful to relate this approach to cell assembly formation due to their mutual force interactions, described in [1]. A particular interest in Joukowski theory application to biomimetic structures [15]- [17] selfassembly description is due to the fact that those structures in some cases possess chirality [21]- [25], while in the framework of the string theory chiral anomalies are possible [26]- [30] with both the strings and membranes (branes) formed from them [31]- [35] demonstrating a sort of chirality.…”